1. Gene
  2. Sesn3 - sestrin 3 Gene

Sesn3 - sestrin 3 Gene

种属: Mus musculus

同用名: SEST3; 5630400E15Rik

基因 ID: 75747 | 基因类型: protein coding

关于 Sesn3

功能概要

Predicted to enable leucine binding activity and oxidoreductase activity, acting on peroxide as acceptor. Involved in several processes, including TORC2 signaling; glucose homeostasis; and regulation of signal transduction. Acts upstream of or within regulation of protein kinase B signaling. Part of TORC2 complex. Orthologous to human SESN3 (sestrin 3). [provided by Alliance of Genome Resources, Apr 2022]

Sesn3 基因产物(1)

mRNA Protein Name
NM_030261.4 NP_084537.2 sestrin-3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables protein binding IPI
IPI: 通过物理相互作用推断
25259925 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in TORC2 signaling IMP
IMP: 通过突变表型推断
25377878 MGI
involved in cellular response to amino acid stimulus IMP
IMP: 通过突变表型推断
25259925 MGI
acts upstream of or within glucose homeostasis IGI
IGI: 通过遗传相互作用推断
22958918 MGI
involved in glucose homeostasis IMP
IMP: 通过突变表型推断
25377878 MGI
involved in negative regulation of TORC1 signaling IMP
IMP: 通过突变表型推断
25259925 MGI
involved in regulation of insulin receptor signaling pathway IMP
IMP: 通过突变表型推断
25377878 MGI
acts upstream of or within regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction IDA
IDA: 通过直接分析推断
22958918 MGI
acts upstream of or within response to insulin IGI
IGI: 通过遗传相互作用推断
22958918 MGI
involved in response to insulin IMP
IMP: 通过突变表型推断
25377878 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of TORC2 complex IDA
IDA: 通过直接分析推断
25377878 MGI
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

sestrin-3

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Sesn3 NCBI NCBI:143686