2. Gene
  3. Nol3 - nucleolar protein 3 (apoptosis repressor with CARD domain) Gene

Nol3 - nucleolar protein 3 (apoptosis repressor with CARD domain) Gene

  • 基因
  • 蛋白
  • 相关产品
  • 直系同源

种属: Mus musculus

同用名: ARC; MYC; NOP; Nop30; B430311C09Rik

基因 ID: 78688 | 基因类型: protein coding

关于 Nol3

功能概要

Enables death effector domain binding activity and death receptor binding activity. Involved in several processes, including cardiac muscle cell apoptotic process; negative regulation of cell death; and regulation of signal transduction. Acts upstream of or within regulation of gene expression; response to hypoxia; and response to injury involved in regulation of muscle adaptation. Located in mitochondrion and sarcoplasm. Is expressed in adrenal gland; brain; lung; metanephros; and musculature. Orthologous to human NOL3 (nucleolar protein 3). [provided by Alliance of Genome Resources, Apr 2022]

Nol3 基因产物(1)

mRNA Protein Name
NM_030152.4 NP_084428.1 nucleolar protein 3
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
enables death effector domain binding IPI
IPI: 通过物理相互作用推断
15383280 MGI
enables death receptor binding IPI
IPI: 通过物理相互作用推断
24440909 MGI
enables protein binding IPI
IPI: 通过物理相互作用推断
15383280 MGI
enables signaling receptor binding IPI
IPI: 通过物理相互作用推断
15383280 MGI
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in blood vessel remodeling IMP
IMP: 通过突变表型推断
22082675 MGI
involved in cardiac muscle cell apoptotic process IMP
IMP: 通过突变表型推断
16505176 MGI
involved in intrinsic apoptotic signaling pathway IMP
IMP: 通过突变表型推断
24312627 MGI
involved in negative regulation of apoptotic process IMP
IMP: 通过突变表型推断
22082675 MGI
involved in negative regulation of cardiac muscle cell apoptotic process IMP
IMP: 通过突变表型推断
16505176 MGI
involved in negative regulation of mitochondrial membrane permeability involved in apoptotic process IMP
IMP: 通过突变表型推断
24312627 MGI
involved in negative regulation of muscle atrophy IMP
IMP: 通过突变表型推断
24312627 MGI
involved in negative regulation of programmed necrotic cell death IMP
IMP: 通过突变表型推断
24440909 MGI
involved in negative regulation of striated muscle cell apoptotic process IMP
IMP: 通过突变表型推断
24312627 MGI
involved in negative regulation of tumor necrosis factor-mediated signaling pathway IMP
IMP: 通过突变表型推断
24440909 MGI
acts upstream of or within regulation of gene expression IMP
IMP: 通过突变表型推断
18782777 MGI
involved in regulation of non-canonical NF-kappaB signal transduction IMP
IMP: 通过突变表型推断
24440909 MGI
acts upstream of or within response to hypoxia IMP
IMP: 通过突变表型推断
18782777 MGI
acts upstream of or within response to injury involved in regulation of muscle adaptation IMP
IMP: 通过突变表型推断
18782777 MGI
involved in response to ischemia IMP
IMP: 通过突变表型推断
16505176 MGI
细胞组分 GO 注释 逻辑证据 参考文献 来源
located in mitochondrion IDA
IDA: 通过直接分析推断
14645204 MGI
located in sarcoplasm IDA
IDA: 通过直接分析推断
14645204 MGI
EXP：通过实验结果推断 IDA：通过直接分析推断 IPI：通过物理相互作用推断 IMP：通过突变表型推断 IGI：通过遗传相互作用推断 IEP：通过表达模式推断
蛋白主名 其他名称

nucleolar protein 3

apoptosis repressor with CARD

Nol3 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Nol3 Q9D1X0 Tra2a Mus musculus Q6PFR5
Pull Down
16249178
种属内
Nol3 Q9D1X0 Tra2a Mus musculus Q6PFR5
Y2H
16249178
种属间: 跨种属相互作用 种属内: 同种属相互作用

相关产品

Pre-clinical Phase
生物活性分子 (3)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS09414 NOL3 Human Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS18487 Nol3 Mouse Pre-designed siRNA Set A Pre-designed Set / 否
HY-RS24969 Nol3 Rat Pre-designed siRNA Set A Pre-designed Set / 否

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Nol3 NCBI NCBI:8996
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