1. Gene
  2. Pggt1b - protein geranylgeranyltransferase type I subunit beta Gene

Pggt1b - protein geranylgeranyltransferase type I subunit beta Gene

种属: Rattus norvegicus

基因 ID: 81746 | 基因类型: protein coding

关于 Pggt1b

功能概要

Enables heterocyclic compound binding activity. Contributes to several functions, including CAAX-protein geranylgeranyltransferase activity; peptide binding activity; and zinc ion binding activity. Involved in several processes, including negative regulation of nitric-oxide synthase biosynthetic process; positive regulation of cell population proliferation; and protein geranylgeranylation. Part of CAAX-protein geranylgeranyltransferase complex. Orthologous to human PGGT1B (protein geranylgeranyltransferase type I subunit beta). [provided by Alliance of Genome Resources, Apr 2022]

Pggt1b 基因产物(1)

mRNA Protein Name
NM_031082.2 NP_112344.1 geranylgeranyl transferase type-1 subunit beta
基因本体论
  • 分子功能
  • 生物过程
  • 细胞组分
分子功能 GO 注释 逻辑证据 参考文献 来源
contributes to CAAX-protein geranylgeranyltransferase activity IDA
IDA: 通过直接分析推断
8089111 RGD
enables CAAX-protein geranylgeranyltransferase activity IDA
IDA: 通过直接分析推断
14609943 RGD
enables heterocyclic compound binding IDA
IDA: 通过直接分析推断
15248757 RGD
contributes to peptide binding IDA
IDA: 通过直接分析推断
9705207 RGD
enables protein binding IPI
IPI: 通过物理相互作用推断
14609943 RGD
contributes to small molecule binding IDA
IDA: 通过直接分析推断
15248757 RGD
contributes to zinc ion binding IDA
IDA: 通过直接分析推断
15248757 RGD
enables zinc ion binding IDA
IDA: 通过直接分析推断
14609943 RGD
生物过程 GO 注释 逻辑证据 参考文献 来源
involved in negative regulation of nitric-oxide synthase biosynthetic process IMP
IMP: 通过突变表型推断
9153192 RGD
involved in positive regulation of cell cycle IMP
IMP: 通过突变表型推断
10544242 RGD
involved in positive regulation of cell population proliferation IMP
IMP: 通过突变表型推断
10544242 RGD
involved in protein geranylgeranylation IDA
IDA: 通过直接分析推断
14609943 RGD
involved in response to cytokine IMP
IMP: 通过突变表型推断
9153192 RGD
细胞组分 GO 注释 逻辑证据 参考文献 来源
part of CAAX-protein geranylgeranyltransferase complex IDA
IDA: 通过直接分析推断
14609943 RGD
EXP:通过实验结果推断 IDA:通过直接分析推断 IPI:通过物理相互作用推断 IMP:通过突变表型推断 IGI:通过遗传相互作用推断 IEP:通过表达模式推断
蛋白主名 其他名称

geranylgeranyl transferase type-1 subunit beta

GGTase-I-beta

geranylgeranyl transferase type I subunit beta

geranylgeranyltransferase type 1 beta

geranylgeranyltransferase type I (GGTase-I)

protein geranylgeranyltransferase type 1 subunit beta

protein geranylgeranyltransferase type I, beta subuni

Pggt1b 蛋白互作信息

分类
蛋白名称 蛋白编号 互作蛋白 互作蛋白种属 互作蛋白编号 实验方法 参考文献
种属内
Pggt1b P53610 Fnta Rattus norvegicus Q04631 18957540
种属内
Pggt1b P53610 Fnta Rattus norvegicus Q04631 15248757
种属间: 跨种属相互作用 种属内: 同种属相互作用

直系同源

种属 基因名 来源 基因 ID
Homo sapiens Pggt1b NCBI NCBI:5229