2. Gene
  3. PPP1R9B - protein phosphatase 1 regulatory subunit 9B Gene

PPP1R9B - protein phosphatase 1 regulatory subunit 9B Gene

  • 基因
  • 蛋白
  • 疾病
  • 相关产品
  • 直系同源

中文名称：蛋白磷酸酶 1 调节亚基 9B

种属: Homo sapiens

同用名: Spn; SPINO; PPP1R6; PPP1R9

基因 ID: 84687 | 基因类型: protein coding

关于 PPP1R9B

Cytogenetic location: 17q21.33 Genomic coordinates (GRCh38): 17:50,133,737-50,150,677 (from NCBI)

This gene has 2 transcripts (splice variants), 272 orthologues and 2 paralogues. Ubiquitous expression in brain (RPKM 26.2), spleen (RPKM 25.4) and 24 other tissues.

功能概要

该基因编码一种支架蛋白，作为蛋白磷酸酶 1a 的调节亚基发挥作用。该基因在树突棘中的表达特别高，表明编码的蛋白质可能在接收来自中枢神经系统的信号中发挥作用。编码的蛋白质具有推定的肿瘤抑制功能，并且已经在肿瘤中观察到表达降低。[RefSeq 提供，2014 年 2 月]

This gene encodes a scaffold protein that functions as a regulatory subunit of protein Phosphatase 1a. Expression of this gene is particularly high in dendritic spines, suggesting that the encoded protein may play a role in receiving signals from the central nervous system. The encoded protein has putative tumor suppressor function and decreased expression has been observed in tumors. [provided by RefSeq, Feb 2014]

PPP1R9B 基因产物(1)

mRNA Protein Name
NM_032595.5 NP_115984.3 neurabin-2

PPP1R9B 蛋白结构

PDZ

PDZ: PDZ domain (Also known as DHR or GLGF) (496 - 576)

  • 0
  • 200
  • 400
  • 600
  • 815 a.a.
蛋白主名 其他名称

neurabin-2

neurabin-II

关联疾病

疾病名称 别名
Limbic Encephalitis
Ventricular Tachycardia, Catecholaminergic Polymorphic, 2

Catecholaminergic Polymorphic Ventricular Tachycardia 2

CPVT2

Vtsip

Bidirectional Tachycardia

Stress-Induced Polymorphic Ventricular Tachycardia

Ventricular Tachycardia, Stress-Induced Polymorphic

Cvpt2

Double Tachycardia Induced By Catecholamines

Malignant Paroxysmal Ventricular Tachycardia

Multifocal Ventricular Premature Beats

Paroxysmal Ventricular Fibrillation

Syncopal Paroxysmal Tachycardia

Syncopal Tachyarythmia

Tachycardia, Ventricular, Catecholaminergic Polymorphic, Type 2

Ventricular Tachycardia, Catecholaminergic Polymorphic, 1

Multifocal Pvcs

Multifocal Premature Ventricular Beats

Paroxysmal Familial Ventricular Fibrillation
Aspirin Allergy

Acetylsalicylic Acid Allergy

Asa Allergy
Schizophrenia

SCZD

Schizophrenia With Or Without An Affective Disorder

Schizophrenia 12

Schizophrenia, Susceptibility To

Schizophrenia-1

Dementia Praecox

Schizophrenia 1
疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

相关产品

Pre-clinical Phase
生物活性分子 (1)
Cat. No. 产品名 作用方式
纯度 是否罕见病
HY-RS11006 PPP1R9B Human Pre-designed siRNA Set A / 否

直系同源

种属 基因名 来源 基因 ID
Rattus norvegicus PPP1R9B RGD RGD:632281
Mus musculus PPP1R9B MGD MGI:2387581
Canis familiaris PPP1R9B VGNC VGNC:44903
Bos taurus PPP1R9B VGNC VGNC:106876
Felis catus PPP1R9B VGNC VGNC:69006
Macaca mulatta PPP1R9B VGNC VGNC:76372
嗨！很高兴为您提供帮助！

尊敬的 MCE 客户您好，
请您选择所在区域，我们将转接对应客服为您服务！

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z

热 A B C F G H J L N Q S T X Y Z