2. 天然产物
  3. 疾病研究领域 植物 黄酮类
  4. 苦苣苔科 炎症/免疫 黄酮
  5. 石吊兰
  6. Lysionotin

Lysionotin 是一种从苦苣苔科中分离出来的类黄酮。Lysionotin 可有效抑制 α-Toxin (一种成孔蛋白) 的表达，并在体内和体外针对金黄色葡萄球菌显示出显著的保护作用。Lysionotin 可用于由金黄色葡萄球菌引起的肺炎的研究。

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Lysionotin Chemical Structure

Lysionotin Chemical Structure

CAS No. : 152743-19-6

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Lysionotin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Lysionotin is a flavonoid isolated from Gesneriaceae family. Lysionotin efficiently inhibit α-Toxin (a pore-forming protein) expression and shows significant protection against S. aureus in vitro and in vivo. Lysionotin has the potential for the treatment of S. aureus induced pneumonia[1].

IC50 & Target

IC50: α-Toxin[1]
CAS 号
结构分类
初始来源
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Room temperature in continental US; may vary elsewhere.
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Please store the product under the recommended conditions in the Certificate of Analysis.
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参考文献

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Lysionotin152743-19-6Othersα-toxinS. aureuspneumoniaInhibitorinhibitorinhibit

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