Prime assembly with linear DNA donors enables large genomic insertions

Affiliations

• 1 RNA Therapeutics Institute, University of Massachusetts Chan Medical School, Worcester, MA, USA.
• 2 Department of Molecular, Cell and Cancer Biology, University of Massachusetts Chan Medical School, Worcester, MA, USA.
• 3 Icahn Genomics Institute, Department of Immunology and Immunotherapy, Department of Oncological Sciences, Department of Genetics and Genomic Sciences, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.
• 4 Li Weibo Institute for Rare Diseases Research, University of Massachusetts Chan Medical School, Worcester, MA, USA.
• 5 Department of Molecular Medicine, University of Massachusetts Chan Medical School, Worcester, Massachusetts, USA.
• 6 Department of Biochemistry and Molecular Biotechnology, University of Massachusetts Chan Medical School, Worcester, MA 01605, USA.