2. Academic Validation
  3. TRIB1 silencing attenuates epilepsy by restoring mitochondrial homeostasis and suppressing microglia-driven neuroinflammation via MAPK pathway inhibition

TRIB1 silencing attenuates epilepsy by restoring mitochondrial homeostasis and suppressing microglia-driven neuroinflammation via MAPK pathway inhibition

  • J Mol Histol. 2025 Sep 5;56(5):295. doi: 10.1007/s10735-025-10580-7.
Chunying Liao 1,  Jie Cao 1,  Hanyi Zeng 1,  Cuiyin Chen 1,  Jianqing Yuan 2
Affiliations

Affiliations

  • 1 Department of Neurology, The First Affiliated Hospital of Gannan Medical University, No.128, Jinling Road, Zhanggong District, Ganzhou, 341000, Jiangxi, China.
  • 2 Department of Neurology, The First Affiliated Hospital of Gannan Medical University, No.128, Jinling Road, Zhanggong District, Ganzhou, 341000, Jiangxi, China. Yjq99157@163.com.
PMID: 40908404 DOI: 10.1007/s10735-025-10580-7
Keywords

Epilepsy; Hub genes; Mitogen-activated protein kinase (MAPK) signaling pathway; Tribbles homolog 1 (TRIB1).

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