ADK/Adenosine Kinase 蛋白, Human (HEK293)

ADK is an enzyme that catalyzes the transfer of gamma-phosphate from adenosine triphosphate (ATP) to adenosine (Ado) to form adenosine monophosphate (AMP). ADK acts as a potential regulator of extracellular adenosine and intracellular adenine nucleotide concentrations. ADK is a therapeutic target for controlling obesity and non-alcoholic fatty liver disease. ADK/Adenosine Kinase Protein, Human (HEK293) is the recombinant human-derived ADK/Adenosine Kinase protein, expressed by HEK293 , with tag free. The total length of ADK/Adenosine Kinase Protein, Human (HEK293) is 345 a.a., with molecular weight of ~38.74 kDa.

Adenosine kinase 是一种催化 γ -磷酸从三磷酸腺苷 (ATP) 转移到腺苷 (Ado) 从而形成单磷酸腺苷 (AMP) 的酶。以 ATP 依赖的方式催化嘌呤核苷腺苷在 5’位置的磷酸化。ADK 可作为细胞外腺苷和细胞内腺嘌呤核苷酸浓度的潜在调节剂。ADK 通过抑制肝细胞脂肪酸氧化和产生肝细胞源性促炎介质，促进脂肪过度沉积和肝脏炎症是控制肥胖和非酒精性脂肪肝疾病的治疗靶点。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

HEK293

Tag Free

AAH03568 (M1-H345)

132  [NCBI]

Approximately 38.74 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris, 300 mM NaCl pH 8.0, 0.5 mM PMSF, 0.5 mM TCEP, 20% glycerol.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.