1. 重组蛋白
  2. Receptor Proteins
  3. G-Protein-Coupled Receptors (GPCRs)
  4. Adenosine Receptor
  5. ADORA2A Protein-VLP, Human (HEK293)

ADORA2A Protein-VLP, Human (HEK293)

目录号: HY-P700899
产品使用指南

ADORA2A 蛋白-VLP 是腺苷受体,通过 G 蛋白激活腺苷酸环化酶。它与细胞质 C 端结构域中的 USP4 和 GAS2L2 直接相互作用表明其具有调节作用。与 DRD4 和 NECAB2 的相互作用意味着参与多种细胞信号传导途径。ADORA2A Protein-VLP, Human (HEK293) 是重组的 ADORA2A 蛋白-VLP,由 HEK293 表达,不带标签。ADORA2A Protein-VLP, Human (HEK293) 全长 412 个氨基酸,分子量为 The target 蛋白 has a predicted MW of。

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描述

ADORA2A Protein-VLP, a receptor for adenosine, activates adenylyl cyclase through G proteins. Its direct interaction with USP4 and GAS2L2 in the cytoplasmic C-terminal domain suggests regulatory roles. Interactions with DRD4 and NECAB2 imply involvement in diverse cellular signaling pathways. ADORA2A Protein-VLP, Human (HEK293) is the recombinant human-derived ADORA2A protein-VLP, expressed by HEK293, with tag free. The total length of ADORA2A Protein-VLP, Human (HEK293) is 412 a.a., with molecular weight of The target protein has a predicted MW of.

研究背景

ADORA2A 蛋白-VLP 作为腺苷受体发挥作用,通过 G 蛋白激活腺苷酸环化酶。其细胞质 C 端结构域直接与 USP4 和 GAS2L2 相互作用,表明在细胞过程中具有潜在的调节作用。此外,ADORA2A 蛋白-VLP 可能与 DRD4 和 NECAB2 相互作用,进一步表明其参与多种细胞信号传导途径。

种属

Human

表达系统

HEK293

标签

Tag Free

蛋白编号

P29274 (M1-S412)

基因 ID

135  [NCBI]

蛋白结构
N-term
ADORA2A-VLP (M1-S412)
Accession # P29274
C-term
同用名
ADORA2A; adenosine A2a receptor; ADORA2; adenosine receptor A2a; RDC8; adenosine A2 receptor; adenosine receptor subtype A2a; hA2aR;
分子量

The target protein has a predicted MW of

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

ADORA2A Protein-VLP, Human (HEK293) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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ADORA2A Protein-VLP, Human (HEK293)
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