Animal-Free FGF-11 isoform 2 蛋白, Human (His)

FGF-11 isoform 2 protein is a member of the fibroblast growth factor family, characterized by broad mitotic and cell survival activities, affecting embryonic development, cell growth, morphogenesis, tissue repair, and tumor growth. Its specific function has not yet been determined, but the expression pattern of its mouse homolog suggests a role in nervous system development. Animal-Free FGF-11 isoform 2 Protein, Human (His) is the recombinant human-derived animal-FreeFGF-11 isoform 2 protein, expressed by E. coli , with C-His labeled tag. The total length of Animal-Free FGF-11 isoform 2 Protein, Human (His) is 166 a.a., with molecular weight of ~19.34 kDa.

该基因编码的蛋白质属于成纤维细胞生长因子（FGF）家族，以其广泛的促有丝分裂和细胞存活活性而闻名，参与胚胎发育、细胞生长、形态发生、组织修复和肿瘤生长等多种生物过程。虽然该基因的具体功能仍有待确定，但其小鼠同源物的表达模式表明其在神经系统发育中发挥作用。选择性剪接导致多种转录变体的产生。这种 FGF-11 亚型 2 蛋白表现出广泛的表达，在肾上腺 (RPKM 9.9)、皮肤 (RPKM 7.0) 和 14 个其他组织中检测到显着水平。

Measure by its ability to induce 3T3 cells proliferation. The ED₅₀ for this effect is <1 ng/mL.

Human

E. coli

C-His

NP_001290389.1 (M1-P166)

2256  [NCBI]

MSLSPEPQLKGIVTKLFCRQGFYLQANPDGSIQGTPEDTSSFTHFNLIPVGLRVVTIQSAKLGHYMAMNAEGLLYSSPHFTAECRFKECVFENYYVLYASALYRQRRSGRAWYLGLDKEGQVMKGNRVKKTKAAAHFLPKLLEVAMYQEPSLHSVPEASPSSPPAP

Approximately 19.34 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a solution containing 1X PBS, pH 7.4.

<0.1 EU per 1 μg of the protein by the LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.