Annexin A5/ANXA5 蛋白, Mouse (His, Myc)

The annexin A5 (ANXA5) protein acts as an anticoagulant, indirectly inhibiting the thromboplastin-specific complex, which is critical in the coagulation cascade. As a monomer, ANXA5 plays a key role in regulating the coagulation pathway, affecting the delicate balance between pro- and anti-coagulant factors. Annexin A5/ANXA5 Protein, Mouse (His, Myc) is the recombinant mouse-derived Annexin A5/ANXA5 protein, expressed by E. coli , with N-10*His, C-Myc labeled tag. The total length of Annexin A5/ANXA5 Protein, Mouse (His, Myc) is 318 a.a., with molecular weight of 43.2 kDa.

膜联蛋白 A5 (ANXA5) 蛋白可作为抗凝剂，作为在凝血级联中至关重要的凝血活酶特异性复合物的间接抑制剂。在结构上，ANXA5 以单体形式存在，就其功能而言，ANXA5 在调节凝血途径的关键成分中发挥着关键作用，从而影响促凝血因子和抗凝血因子之间的微妙平衡。此外，ANXA5 表现出与 ATRX 和 EIF5B 的结合相互作用，表明它除了在凝血中发挥作用之外，还参与多种细胞过程。这些多方面的属性强调了 ANXA5 在细胞调节中的重要性及其对止血和更广泛的细胞功能的潜在影响。

Mouse

E. coli

N-10*His;C-Myc

P48036 (A2-D319)

11747

43.2 kDa

Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.22 μm filtered solution of 20 mM Tris-HCl, 0.5 M NaCl, 6% Trehalose, pH 8.0.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.