APOA1BP 蛋白, Human (HEK293, His)

APOA1BP protein plays a crucial role in cellular processes by catalyzing the S- and R-type epimerization of NAD(P)HX, a protein that results from enzymatic or heat-dependent hydration. Damaged form of NAD(P)H. This catalytic activity is a prerequisite for the subsequent action of S-specific NAD(P)H hydrate dehydratase, enabling the repair of both epimers of NAD(P)HX. APOA1BP Protein, Human (HEK293, His) is the recombinant human-derived APOA1BP protein, expressed by HEK293 , with C-His labeled tag. The total length of APOA1BP Protein, Human (HEK293, His) is 288 a.a., with molecular weight of ~30.6 KDa.

APOA1BP，也称为 NAXE (NAD(P)HX 差向异构酶)，催化 NAD(P)HX 的 S 和 R 形式的差向异构化，NAD(P)HX 是由酶促或热依赖性水合作用引起的 NAD(P)H 受损形式。这种差向异构化过程是 S 特异性 NAD(P)H 水合物脱水酶后续修复的先决条件，从而可以恢复 NAD(P)HX 的两个差向异构体。除了在核苷酸代谢中的作用之外，APOA1BP 还通过加速胆固醇从内皮细胞流出至高密度脂蛋白 (HDL) 来在胆固醇稳态中发挥作用。这一功能表明 APOA1BP 在血管生成中发挥调节作用，将其酶活性与血管形成过程联系起来。它必须强调 APOA1BP 在核苷酸代谢和胆固醇稳态中的双重功能，强调其对与血管生成相关的细胞过程的潜在影响。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

HEK293

C-His

Q8NCW5 (M1-Q288)

128240  [NCBI]

Approximately 30.6 kDa.

Greater than 95% as determined by reducing SDS-PAGE.

溶液

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.