Apolipoprotein A-I/APOA1 蛋白, Mouse (HEK293, His)

The apolipoprotein AI (APOA1) protein is key to reverse cholesterol transport, promoting tissue efflux, and serves as an important cofactor for lecithin cholesterol acyltransferase (LCAT), promoting cholesterol excretion. As a homodimer, APOA1 is a component of the sperm activating protein complex (SPAP), interacts with APOA1BP, CLU, NDRG1, SCGB3A2, NAXE and YJEFN3, exhibiting multiple molecular associations. Apolipoprotein A-I/APOA1 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Apolipoprotein A-I/APOA1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Apolipoprotein A-I/APOA1 Protein, Mouse (HEK293, His) is 246 a.a., with molecular weight of 27-31 kDa.

载脂蛋白 AI (APOA1) 蛋白在胆固醇逆向转运中发挥关键作用，促进其从组织流出，并作为卵磷脂胆固醇酰基转移酶 (LCAT) 的关键辅助因子，促进胆固醇从组织排泄至肝脏。该蛋白质以同二聚体形式存在，是精子激活蛋白复合物 (SPAP) 的一部分，该复合物包括 APOA1、免疫球蛋白重链、免疫球蛋白轻链和白蛋白。APOA1 还与 APOA1BP 和 CLU 相互作用，促成其多样化的分子关联。此外，它还与 NDRG1、SCGB3A2、NAXE 和 YJEFN3 结合，进一步强调了它参与胆固醇代谢以外的各种细胞过程，包括精子活力和蛋白质复合物相互作用。

Mouse

HEK293

C-His

Q00623 (W19-Q264)

11806  [NCBI]

27-31 kDa

Greater than 90% as determined by reducing SDS-PAGE

溶液.

Supplied as a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.