Atrial natriuretic peptide receptor 2/NPR2, Human (His)

Atrial natriuretic peptide receptor 2 (NPR2) serves as the receptor for C-type natriuretic peptide NPPC/CNP, activating guanylate cyclase upon ligand binding. NPR2 potentially regulates skeletal growth, indicating involvement in bone development. Its interaction with C-type natriuretic peptide highlights its significance in mediating cellular responses, especially in signaling pathways influencing skeletal growth dynamics. Atrial natriuretic peptide receptor 2/NPR2, Human (His) is the recombinant human-derived Atrial natriuretic peptide receptor 2/NPR2, expressed by P. pastoris , with N-His labeled tag. The total length of Atrial natriuretic peptide receptor 2/NPR2, Human (His) is 436 a.a., with molecular weight of ~51.0 kDa.

心房钠尿肽受体 2 (NPR2) 作为 C 型钠尿肽 NPPC/CNP 激素的受体发挥作用，在配体结合后表现出鸟苷酸环化酶活性。这种受体在骨骼生长的调节中发挥着潜在的作用，表明它参与了控制骨骼发育和维持的过程。NPR2 和 C 型利尿钠肽之间的相互作用凸显了其在介导细胞对该激素反应中的重要性，特别是在影响骨骼生长动力学的信号通路背景下。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Human

P. pastoris

N-His

P20594 (R23-I458)

4882  [NCBI]

RNLTLAVVLPEHNLSYAWAWPRVGPAVALAVEALGRALPVDLRFVSSELEGACSEYLAPLSAVDLKLYHDPDLLLGPGCVYPAASVARFASHWRLPLLTAGAVASGFSAKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPHYFTIEGVFEALQGSNLSVQHQVYAREPGGPEQATHFIRANGRIVYICGPLEMLHEILLQAQRENLTNGDYVFFYLDVFGESLRAGPTRATGRPWQDNRTREQAQALREAFQTVLVITYREPPNPEYQEFQNRLLIRAREDFGVELGPSLMNLIAGCFYDGILLYAEVLNETIQEGGTREDGLRIVEKMQGRRYHGVTGLVVMDKNNDRETDFVLWAMGDLDSGDFQPAAHYSGAEKQIWWTGRPIPWVKGAPPSDNPPCAFDLDDPSCDKTPLSTLAI

Approximately 51.0 kDa

• 
  Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from 0.22 μm filtered solution in PBS, pH 7.4. or10 mM Tris-HCl, 1 mM EDTA, 6% Trehalose, pH 8.0.

<1.0 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.