1. 重组蛋白
  2. Cytokines and Growth Factors CD Antigens Biotinylated Proteins
  3. TNF Superfamily B Cell CD Proteins Macrophage CD Proteins
  4. TNF Superfamily Ligands CD257/BAFF
  5. B-cell Activating Factor (BAFF)
  6. BAFF/TNFSF13B 蛋白, Human (Biotinylated, HEK293, His-Avi)

BAFF/TNFSF13B 蛋白, Human (Biotinylated, HEK293, His-Avi)

目录号: HY-P78066
COA 产品使用指南

BAFF/TNFSF13B 蛋白是一种细胞因子,可与 TNFRSF13B/TACI 和 TNFRSF17/BCMA 结合,与 TNFSF13/APRIL 一起形成关键的配体-受体途径。这些相互作用在刺激 B 细胞和 T 细胞功能以及调节体液免疫方面发挥着至关重要的作用。BAFF/TNFSF13B 蛋白, Human (Biotinylated, HEK293, His-Avi) 是重组的 BAFF/TNFSF13B 蛋白,由 HEK293 表达,带有 N-His, N-Avi 标签。BAFF/TNFSF13B 蛋白, Human (Biotinylated, HEK293, His-Avi) 全长 145 个氨基酸,分子量为 55-68 kDa。

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重组蛋白定制服务

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     可免费申领三个不同产品的试用装。

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规格 价格 是否有货 数量
20 μg ¥2450 In-stock
50 μg ¥5400 In-stock
100 μg ¥9180 询价
> 100 μg   询价  

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描述

BAFF/TNFSF13B protein is a cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA, forming a key ligand-receptor pathway together with TNFSF13/APRIL. These interactions play a crucial role in stimulating B-cell and T-cell function and regulating humoral immunity. BAFF/TNFSF13B Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived BAFF/TNFSF13B protein, expressed by HEK293 , with N-His, N-Avi labeled tag. The total length of BAFF/TNFSF13B Protein, Human (Biotinylated, HEK293, His-Avi) is 145 a.a., with molecular weight of 55-68 kDa.

研究背景

BAFF/TNFSF13B 蛋白是一种细胞因子,可与 TNFRSF13B/TACI 和 TNFRSF17/BCMA 结合,与 TNFSF13/APRIL 一起形成关键的配体-受体途径。这些相互作用在刺激 B 细胞和 T 细胞功能以及调节体液免疫方面发挥着至关重要的作用。值得注意的是,第三种 B 细胞特异性受体 BAFFR/BR3 参与促进成熟 B 细胞的存活并促进 B 细胞反应。这个复杂的网络强调了BAFF/TNFSF13B 在协调免疫反应中的重要性。此外,BAFF/TNFSF13B 的亚型 2 似乎通过抑制亚型 1 的分泌和生物活性发挥调节作用。这些亚型之间的动态相互作用进一步有助于对 BAFF/TNFSF13B 介导的免疫过程进行细致的控制。

生物活性

1. Immobilized Biotinylated Human BAFF (Trimer) at 2 μg/mL (100 μL/Well) on the plate. Dose response curve for Human BAFFR hFc with the EC50 of 0.29 μg/mL determined by ELISA.
2. Immobilized Human BAFFR, hFc Tag at 5 μg/mL (100 μL/Well) on the plate. Dose response curve for Biotinylated Human BAFF(Trimer), His Tag with the EC50 of 7.7 ng/mL determined by ELISA.

种属

Human

表达系统

HEK293

标签

N-His;N-Avi

蛋白编号

Q9Y275 (T141-L285)

基因 ID
蛋白结构
N-term
His-Avi
BAFF (T141-L285)
Accession # Q9Y275
C-term
同用名
BAFF; BLyS; CD257; TNFSF13B; TNFSF20; DTL; TALL1; TALL-1delta BAFF; TALL1Delta4 BAFF; THANK; ZTNF4; TALL-1
氨基酸序列

TVTQDCLQLIADSETPTIQKGSYTFVPWLLSFKRGSALEEKENKILVKETGYFFIYGQVLYTDKTYAMGHLIQRKKVHVFGDELSLVTLFRCIQNMPETLPNNSCYSAGIAKLEEGDELQLAIPRENAQISLDGDVTFFGALKLL

分子量

55-68 kDa

纯度

Greater than 95% as determined by Tris-Bis PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 5% trehalose is added as protectant before lyophilization.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
BAFF/TNFSF13B Protein, Human (Biotinylated, HEK293, His-Avi)
目录号:
HY-P78066
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