1. 重组蛋白
  2. Cytokines and Growth Factors
  3. EGF Superfamily
  4. Betacellulin
  5. Betacellulin/BTC 蛋白, Mouse (HEK293, His-hFc)

Betacellulin/BTC 蛋白, Mouse (HEK293, His-hFc)

目录号: HY-P75478
产品使用指南

Betacellulin/BTC 蛋白是一种对 EGFR、ERBB4 和其他 EGF 受体家族成员具有亲和力的生长因子,作为单体对视网膜色素上皮细胞和血管平滑肌细胞发挥有效的促有丝分裂作用。其分子活性涉及与 EGFR 和 ERBB4 的相互作用,有助于细胞信号传导和调节。Betacellulin/BTC 蛋白, Mouse (HEK293, His-hFc) 是重组的 Betacellulin/BTC 蛋白,由 HEK293 表达,带有 C-hFc, C-His 标签。Betacellulin/BTC 蛋白, Mouse (HEK293, His-hFc) 全长 87 个氨基酸,分子量为 50-55 kDa。

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描述

Betacellulin/BTC Protein, a growth factor with affinity for EGFR, ERBB4, and other EGF receptor family members, exerts potent mitogenic effects on retinal pigment epithelial cells and vascular smooth muscle cells as a monomer. Its molecular activity involves interactions with EGFR and ERBB4, contributing to cellular signaling and regulation. Betacellulin/BTC Protein, Mouse (HEK293, His-hFc) is the recombinant mouse-derived Betacellulin/BTC protein, expressed by HEK293 , with C-hFc, C-His labeled tag. The total length of Betacellulin/BTC Protein, Mouse (HEK293, His-hFc) is 87 a.a., with molecular weight of 50-55 kDa.

研究背景

Betacellulin/BTC 蛋白是一种生长因子,对 EGFR、ERBB4 和 EGF 受体家族的其他成员具有亲和力。它作为单体对视网膜色素上皮细胞和血管平滑肌细胞发挥有效的促有丝分裂作用。其分子活性涉及与 EGFR 和 ERBB4 的相互作用,有助于其在细胞信号传导和调节中的作用。

种属

Mouse

表达系统

HEK293

标签

C-hFc;C-His

蛋白编号

Q05928 (D32-Q118)

基因 ID

12223  [NCBI]

蛋白结构
N-term
BTC (D32-Q118)
Accession # Q05928
hFc-His
C-term
同用名
Btc; Betacellulin; Betacellulin epidermal growth factor family member
分子量

50-55 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

Betacellulin/BTC Protein, Mouse (HEK293, His-hFc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
Betacellulin/BTC Protein, Mouse (HEK293, His-hFc)
目录号:
HY-P75478
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