2. 重组蛋白
  3. CAR-T related Proteins CD Antigens
  4. T Cell CD Proteins B Cell CD Proteins Stem Cell CD Proteins
  5. CD38
  6. CD38 蛋白, Mouse (HEK293, Fc)

CD38 蛋白, Mouse (HEK293, Fc)

目录号: HY-P70044
产品使用指南

CD38 蛋白在合成重要的第二信使环 ADP-核糖 (cADPR) 和烟酸腺嘌呤二核苷酸磷酸 (NAADP) 方面发挥着关键作用。cADPR 参与葡萄糖诱导的胰岛素分泌，NAADP 充当钙动员剂。CD38 还表现出 cADPR 水解酶活性，展示了其多功能性。CD38 蛋白, Mouse (HEK293, Fc) 是重组的 CD38 蛋白，由 HEK293 表达，带有 C-hFc 标签。CD38 蛋白, Mouse (HEK293, Fc) 全长 260 个氨基酸，分子量为 70-90 kDa。

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100 μg   询价  

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描述

CD38 protein is pivotal in synthesizing crucial second messengers, cyclic ADP-ribose (cADPR) and nicotinate-adenine dinucleotide phosphate (NAADP). cADPR participates in glucose-induced insulin secretion, and NAADP functions as a calcium mobilizer. CD38 also displays cADPR hydrolase activity, showcasing its multifunctionality. CD38 Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived CD38 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD38 Protein, Mouse (HEK293, Fc) is 260 a.a., with molecular weight of 70-90 kDa.
研究背景

CD38 蛋白在合成两个重要的第二信使：环 ADP-核糖 (cADPR) 和烟酸腺嘌呤二核苷酸磷酸 (NAADP) 方面发挥着至关重要的作用。cADPR 作为第二信使参与葡萄糖诱导的胰岛素分泌，而 NAADP 作为钙动员剂。此外，CD38 表现出 cADPR 水解酶活性，进一步增强了其功能的多功能性。
种属

Mouse
表达系统

HEK293
标签

C-hFc
蛋白编号

P56528 (L45-T304)
基因 ID
蛋白结构
N-term
CD38 (L45-T304)
Accession # P56528
hFc
C-term
同用名
rMuADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1, Fc; ADP-ribosyl cyclase 1; cyclic ADP-ribose hydrolase; CD38; T10
氨基酸序列

LRPRSLLVWTGEPTTKHFSDIFLGRCLIYTQILRPEMRDQNCQEILSTFKGAFVSKNPCNITREDYAPLVKLVTQTIPCNKTLFWSKSKHLAHQYTWIQGKMFTLEDTLLGYIADDLRWCGDPSTSDMNYVSCPHWSENCPNNPITVFWKVISQKFAEDACGVVQVMLNGSLREPFYKNSTFGSVEVFSLDPNKVHKLQAWVMHDIEGASSNACSSSSLNELKMIVQKRNMIFACVDNYRPARFLQCVKNPEHPSCRLNT

分子量

70-90 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

CD38 Protein, Mouse (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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