1. Gene
  2. Cd38 - CD38 antigen Gene

Cd38 - CD38 antigen Gene

中文名称:CD38 抗原

种属: Mus musculus

同用名: I-19; ADPRC 1; Cd38-rs1

基因 ID: 12494 | 基因类型: protein coding

关于 Cd38

Chromosome 5: 44,025,895-44,069,717 forward strand.GRCm39:CM000998.3

This gene has 2 transcripts (splice variants), 281 orthologues, 1 paralogue and is associated with 23 phenotypes. Broad expression in large intestine adult (RPKM 24.5), colon adult (RPKM 16.5) and 21 other tissues.


该基因编码一种非谱系限制的 II 型跨膜糖蛋白,可合成和水解环腺苷 5'-二磷酸核糖,一种细胞内钙离子动员信使。可溶性蛋白的释放和膜结合蛋白内化的能力表明了该蛋白的细胞外和细胞内功能。该蛋白有一个 N 端胞质尾部、一个跨膜结构域和一个带有四个 N 糖基化位点的 C 端胞外区。该基因缺陷的基因敲除小鼠表现出改变的体液免疫反应。此外,敲除小鼠表现出更高的运动活性以及在养育和社交行为方面的缺陷。 [RefSeq 提供,2015 年 9 月]

This gene encodes a non-lineage-restricted, type II transmembrane glycoprotein that synthesizes and hydrolyzes cyclic adenosine 5'-diphosphate-ribose, an intracellular calcium ion mobilizing messenger. The release of soluble protein and the ability of membrane-bound protein to become internalized indicate both extracellular and intracellular functions for the protein. This protein has an N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites. Knockout mice deficient for this gene display altered humoral immune responses. In addition, knockout mice exhibit higher locomotor activity and defects in nurturing and social behaviors. [provided by RefSeq, Sep 2015]

Cd38 基因产物(1)

mRNA Protein Name
NM_007646.6 NP_031672.2 ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

Cd38 蛋白结构


Rib_hydrolayse: pfam02267 (58 - 287)

  • 0
  • 100
  • 200
  • 304 a.a.
蛋白主名 其他名称

ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1

2'-phospho-ADP-ribosyl cyclase

2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase

2'-phospho-cyclic-ADP-ribose transferase

ADP-ribosyl cyclase 1

NIM-R5 antigen

cADPr hydrolase 1

cyclic ADP-ribose hydrolase 1

重组 Cd38 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70044 CD38 Protein, Mouse (HEK293, Fc) P56528 (L45-T304) ≥95%
HY-P72732 CD38 Protein, Mouse (HEK293, His) P56528 (L45-T304) ≥95%


种属 基因名 来源 基因 ID
Homo sapiens Cd38 NCBI NCBI:952
Macaca fascicularis Cd38 NCBI NCBI:102126394
Leporidae Cd38 NCBI
Rattus norvegicus Cd38 NCBI NCBI:25668