CD97 蛋白, Human (HEK293, hFc)

CD97, a receptor crucial for leukocyte migration, participates in adhesion and signaling during early leukocyte activation. Forming a heterodimer with a large extracellular alpha subunit and a seven-transmembrane beta subunit, CD97 interacts with complement decay-accelerating factor (DAF). The largest isoform (isoform 1) specifically engages with chondroitin sulfate, showcasing its diverse roles in cellular processes. CD97 Protein, Human (HEK293, hFc) is the recombinant human-derived CD97 protein, expressed by HEK293 , with C-hFc labeled tag. The total length of CD97 Protein, Human (HEK293, hFc) is 378 a.a., with molecular weight of 100-110 kDa.

CD97 是一种可能参与早期白细胞激活过程中粘附和信号传导过程的受体，在促进白细胞迁移中发挥着至关重要的作用。该受体形成异二聚体，包含与七跨膜β亚基非共价连接的大细胞外α亚基。CD97 与补体衰变加速因子 (DAF) 相互作用，最大的异构体（异构体 1）与硫酸软骨素特异性结合，突出了其在细胞过程中的多种相互作用。

Measured by its binding ability in a functional ELISA. Immobilized human CD55 at 2 μg/mL (100 μl/well) can bind human CD97 with a linear range of 1.28-32 ng/mL.

Human

HEK293

C-hFc

P48960/NP_001775 (Q21-Q398)

976  [NCBI]

MGGRVFLAFCVWLTLPGAETQDSRGCARWCPQNSSCVNATACRCNPGFSSFSEIITTPTETCDDINECATPSKVSCGKFSDCWNTEGSYDCVCSPGYEPVSGAKTFKNESENTCQDVDECSSGQHQCDSSTVCFNTVGSYSCRCRPGWKPRHGIPNNQKDTVCEDMTFSTWTPPPGVHSQTLSRFFDKVQDLGRDSKTSSAEVTIQNVIKLVDELMEAPGDVEALAPPVRHLIATQLLSNLEDIMRILAKSLPKGPFTYISPSNTELTLMIQERGDKNVTMGQSSARMKLNWAVAAGAEDPGPAVAGILSIQNMTTLLANASLNLHSKKQAELEEIYESSIRGVQLRRLSAVNSIFLSHNNTKELNSPILFAFSHLESSDGEAGRDPPAKDVMPGPRQ

100-110 kDa

Greater than 90% as determined by reducing SDS-PAGE.

溶液

Supplied as sterile PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.