Delta-like 蛋白 3/DLL3 蛋白, Mouse (HEK293, His)

Delta-like protein 3 (DLL3) inhibits primary neurogenesis and directs neurons towards specific differentiation pathways. It also contributes to the formation of somite boundaries in the paraxial mesoderm segmentation. DLL3's importance in developmental processes is highlighted by its ability to bind and activate Notch-1 or other Notch receptors. Delta-like protein 3/DLL3 Protein, Mouse (HEK293, His) is the recombinant mouse-derived Delta-like protein 3/DLL3 protein, expressed by HEK293 , with C-His labeled tag. The total length of Delta-like protein 3/DLL3 Protein, Mouse (HEK293, His) is 464 a.a., with molecular weight of 52-60 kDa.

Delta 样蛋白 3 (DLL3) 作为初级神经发生的抑制剂发挥作用，并且可能在沿着特定分化途径转移神经元方面发挥关键作用。此外，DLL3 参与轴旁中胚层分割过程中体节边界的形成。它结合并激活 Notch-1 或其他 Notch 受体的能力强调了它在调节发育过程中的重要性。

Immobilized Mouse DLL3, His Tag at 5 μg/ml (100 μl/well) on the plate. Dose response curve for Anti-DLL3 Antibody, hFc Tag with the EC₅₀ of 7.7 ng/ml determined by ELISA.

Mouse

HEK293

C-His

O88516 (A25-R488)

13389  [NCBI]

52-60 kDa

Greater than 95% as determined by Tris-Bis PAGE.

无菌粉末.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. Normally 5% trehalose is added as protectant before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.