Ephrin-A2/EFNA2 蛋白, Rat (HEK293, Fc)

Ephrin-A2 (EFNA2) is a member of the ephrin family. Ephrin-A2/EFNA2 Protein, Rat (HEK293, Fc) is the recombinant rat-derived Ephrin-A2/EFNA2 protein, expressed by HEK293 , with C-hFc labeled tag.

Ephrin-A2，也称为 EFNA2，是肝配蛋白家族的成员，既充当配体又充当受体，在细胞通讯和组织发育中发挥着至关重要的作用。作为一种跨膜蛋白，Ephrin-A2 通过与邻近细胞上的 Eph 受体相互作用来参与双向信号传导，触发调节多种细胞过程的细胞内级联反应。Ephrin-A2 尤其参与神经元发育过程中的轴突引导，有助于神经系统的精确连接。此外，它在血管生成中发挥作用，影响血管发育和内皮细胞行为。Ephrin-A2 的多方面功能强调了其在协调复杂细胞行为中的重要性，并强调了其参与各种生理和病理过程。了解 Ephrin-A2 控制的分子机制对于阐明其在神经生物学、心血管发育和其他医学领域的潜在影响至关重要。

Measured by its ability to inhibit proliferation of PC-3 human prostate cancer cells. The ED₅₀ for this effect is 26.55 ng/mL, corresponding to a specific activity is 3.766×10⁴ units/mg.

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  Measured by its ability to inhibit proliferation of PC-3 human prostate cancer cells. The ED₅₀ for this effect is 26.55 ng/mL, corresponding to a specific activity is 3.766×10⁴ units/mg.

Rat

HEK293

C-hFc

F1MA19 (R21-S183)

84358  [NCBI]

Partial

RNEDPARANADRYAVYWNRSNPRFQVSAVGDGGGYTVEVSINDYLDIYCPHYGAPLPPAERMERYILYMVNGEGHASCDHRQRGFKRWECNRPAAPGGPLKFSEKFQLFTPFSLGFEFRPGHEYYYISATPPNLVDRPCLRLKVYVRPTNETLYEAPEPIFTS

Approximately 55 kDa.

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.