1. 重组蛋白
  2. Cytokines and Growth Factors
  3. FGF Family
  4. Fibroblast Growth Factor
  5. FGF-22
  6. FGF-22 蛋白, Human (His-SUMO)

FGF-22 蛋白, Human (His-SUMO)

目录号: HY-P700494
产品使用指南

FGF-22 蛋白在生理过程中多方面影响禁食反应、葡萄糖稳态、脂肪分解和脂肪生成。它刺激体外细胞增殖,可能有助于头发发育。在功能上,FGF-22FGFR1FGFR2 形成复合物,是 FGF 信号通路的组成部分。与 FGFBP1 的相互作用凸显了其在调控细胞和代谢活动的精细调节网络中的作用。FGF-22 蛋白, Human (His-SUMO) 是重组的 FGF-22 蛋白,由 E. coli 表达,带有 N-SUMO, N-6*His 标签。FGF-22 蛋白, Human (His-SUMO) 全长 148 个氨基酸,分子量为 30.1 kDa。

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描述

FGF-22 Protein, multifaceted in physiological processes, influences fasting response, glucose homeostasis, lipolysis, and lipogenesis. It stimulates in vitro cell proliferation and may contribute to hair development. Functionally, FGF-22 forms complexes with FGFR1 and FGFR2, integral to FGF signaling pathways. Interactions with FGFBP1 highlight its role in finely tuned regulatory networks governing cellular and metabolic activities. FGF-22 Protein, Human (His-SUMO) is the recombinant human-derived FGF-22 protein, expressed by E. coli, with N-SUMO, N-6*His labeled tag. The total length of FGF-22 Protein, Human (His-SUMO) is 148 a.a., with molecular weight of 30.1 kDa.

研究背景

FGF-22 是一种多方面的蛋白质,复杂地参与多种生理过程,包括禁食反应、葡萄糖稳态、脂肪分解和脂肪生成。除了其代谢作用之外,FGF-22 还具有刺激体外细胞增殖的能力,突出了其对细胞动力学的影响。此外,该蛋白质可能有助于头发发育的复杂过程。从功能上讲,FGF-22 参与重要的分子相互作用,与 FGFR1 和 FGFR2(FGF 信号通路的重要参与者)形成复合物。此外,它与 FGFBP1 相互作用,进一步强调其参与调控各种细胞和代谢活动的精细调节网络。

种属

Human

表达系统

E. coli

标签

N-SUMO;N-6*His

蛋白编号

Q9HCT0 (T23-S170)

基因 ID
蛋白结构
N-term
6*His-SUMO
FGF-22 (T23-S170)
Accession # Q9HCT0
C-term
同用名
Fibroblast growth factor 22; FGF22; FGF-22
氨基酸序列

TPSASRGPRSYPHLEGDVRWRRLFSSTHFFLRVDPGGRVQGTRWRHGQDSILEIRSVHVGVVVIKAVSSGFYVAMNRRGRLYGSRLYTVDCRFRERIEENGHNTYASQRWRRRGQPMFLALDRRGGPRPGGRTRRYHLSAHFLPVLVS

分子量

30.1 kDa

纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

FGF-22 Protein, Human (His-SUMO) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
FGF-22 Protein, Human (His-SUMO)
目录号:
HY-P700494
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