FGF22 - fibroblast growth factor 22 Gene

中文名称：成纤维细胞生长因子 22

种属: Homo sapiens

关于 FGF22

功能概要

该基因编码的蛋白质是成纤维细胞生长因子 (FGF) 家族的成员。 FGF 家族成员具有广泛的促有丝分裂和细胞存活活性，并参与多种生物过程，包括胚胎发育、细胞生长、形态发生、组织修复、肿瘤生长和侵袭。该基因的小鼠同系物被发现优先在毛囊的内根鞘中表达，这表明它在毛发发育中发挥作用。可变剪接导致多个转录本变体。[RefSeq 提供，2014 年 7 月]

The protein encoded by this gene is a member of the Fibroblast Growth Factor (FGF) family. FGF Family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]