2. 重组蛋白
  3. Immune Checkpoint Proteins Biotinylated Proteins
  4. Inhibitory Checkpoint Molecules
  5. FGL-2
  6. FGL2 蛋白, Mouse (Biotinylated, HEK293, His-Avi, Flag)

FGL2 蛋白, Mouse (Biotinylated, HEK293, His-Avi, Flag)

目录号: HY-P700988
产品使用指南

FGL2是凝血级联中的关键酶，在凝血酶原向凝血酶的转化中起关键作用，反映了其对止血和凝血过程的重要贡献。在结构上，FGL2 形成以二硫键为特征的同源四聚体，这有助于其在凝血酶生成的复杂过程中的功能完整性和催化活性。FGL2 蛋白, Mouse (Biotinylated, HEK293, His-Avi, Flag) 是重组的 FGL2 蛋白，由 HEK293 表达，带有 C-Avi, N-His, N-Flag 标签。FGL2 蛋白, Mouse (Biotinylated, HEK293, His-Avi, Flag) 全长 236 个氨基酸，分子量为 40-50 kDa。

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

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描述

FGL2 is a key enzyme in the coagulation cascade and plays a key role in the conversion of prothrombin to thrombin, reflecting its important contribution to hemostasis and coagulation processes. Structurally, FGL2 forms homotetramers characterized by disulfide bonds that contribute to its functional integrity and catalytic activity in the complex process of thrombin generation. FGL2 Protein, Mouse (Biotinylated, HEK293, His-Avi, Flag) is the recombinant mouse-derived FGL2 protein, expressed by HEK293 , with C-Avi, N-His, N-Flag labeled tag. The total length of FGL2 Protein, Mouse (Biotinylated, HEK293, His-Avi, Flag) is 236 a.a., with molecular weight of 40-50 kDa.
研究背景

FGL2（纤维蛋白原样蛋白 2）是参与凝血途径的关键酶，通过将凝血酶原转化为凝血酶来发挥其功能。这种转化是血液凝固过程中的关键步骤，在维持止血方面发挥着基础作用。在结构上，FGL2 形成同源四聚体，表明四个相同亚基的组装。该四聚体结构的完整性通过亚基之间的二硫键保持。同源四聚体排列表明了一种合作机制，可能增强 FGL2 凝血酶原至凝血酶转化活性的效率。正在进行的研究可能会揭示 FGL2 在凝血级联中的具体调节机制和生理学影响的更多见解。
种属

Mouse
表达系统

HEK293
标签

C-Avi;N-His;N-Flag
蛋白编号

P12804 (P197-P432)
基因 ID

14190  [NCBI]
同用名
Fibroleukin; pT49; FGL2; fibrinogen-like 2;
分子量

40-50 kDa
纯度

Greater than 95% as determined by reducing SDS-PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

FGL2 Protein, Mouse (Biotinylated, HEK293, His-Avi, Flag) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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