1. 重组蛋白
  2. Cytokines and Growth Factors
  3. Chemokine & Receptors
  4. CX3CL1
  5. Fractalkine/CX3CL1 蛋白, Cynomolgus/Rhesus Macaque (HEK293, His)

Fractalkine/CX3CL1 蛋白, Cynomolgus/Rhesus Macaque (HEK293, His)

目录号: HY-P76939
产品使用指南

Fractalkine/CX3CL1 蛋白是一种趋化因子,可结合 CX3CR1 和整合素 ITGAV:ITGB3 和 ITGA4:ITGB1。它调节免疫反应、炎症、粘附、趋化性和白细胞迁移。它通过 CX3CR1 依赖性和非依赖性途径激活整合素,结合 CX3CR1 的位点 1 和不结合 CX3CR1 的位点 2。可溶性 Fractalkine/CX3CL1 吸引 T 细胞和单核细胞,而不是中性粒细胞。Fractalkine/CX3CL1 蛋白, Cynomolgus/Rhesus Macaque (HEK293, His) 是重组的 Fractalkine/CX3CL1 蛋白,由 HEK293 表达,带有 C-His 标签。Fractalkine/CX3CL1 蛋白, Cynomolgus/Rhesus Macaque (HEK293, His) 全长 100 个氨基酸,分子量约为 ~10.1 KDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

Fractalkine/CX3CL1 protein, a chemokine, binds CX3CR1 and integrins ITGAV:ITGB3 and ITGA4:ITGB1. It regulates immune response, inflammation, adhesion, chemotaxis, and leukocyte migration. It activates integrins via CX3CR1-dependent and -independent pathways, binding to site 1 with CX3CR1 and site 2 without CX3CR1. Soluble Fractalkine/CX3CL1 attracts T-cells and monocytes, not neutrophils. Fractalkine/CX3CL1 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is the recombinant Rhesus Macaque-derived Fractalkine/CX3CL1 protein, expressed by HEK293 , with C-His labeled tag. The total length of Fractalkine/CX3CL1 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) is 100 a.a., with molecular weight of ~10.1 KDa.

研究背景

Fractalkine/CX3CL1 是一种趋化因子,可作为 CX3CR1 和整合素 ITGAV:ITGB3 和 ITGA4:ITGB1 的配体。其通过 CX3CR1-CX3CL1 通路的信号传导在不同的组织区室中发挥各种作用,包括免疫反应、炎症、细胞粘附和趋化性。它调节内皮细胞的白细胞粘附和迁移,并可以以 CX3CR1 依赖性和 CX3CR1 独立的方式激活整合素。在存在 CX3CR1 的情况下,它通过与经典配体结合位点(位点 1)结合来激活整合素,而在不存在 CX3CR1 的情况下,它与整合素中不同于位点 1 的第二个位点(位点 2)结合,并增强其他整合素配体与位点 1 的结合。Fractalkine/CX3CL1 的可溶形式可作为 T 细胞和单核细胞的趋化因子,但不能作为中性粒细胞的趋化因子。

种属

Rhesus Macaque

表达系统

HEK293

标签

C-His

蛋白编号

P78423 (M1-G100)

基因 ID
蛋白结构
N-term
Fractalkine (M1-G100)
Accession # P78423
His
C-term
同用名
Fractalkine; C-X3-C motif chemokine 1; Neurotactin; CX3CL1; FKN; NTT; SCYD1
分子量

Approximately 10.1 kDa.

纯度

Greater than 95% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

Fractalkine/CX3CL1 Protein, Cynomolgus/Rhesus Macaque (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
Fractalkine/CX3CL1 Protein, Cynomolgus/Rhesus Macaque (HEK293, His)
目录号:
HY-P76939
需求量: