1. 重组蛋白
  2. Enzymes & Regulators
  3. Lyases (EC 4)
  4. GAD1/GAD67 蛋白, Human (sf9, His)

GAD1/GAD67 蛋白, Human (sf9, His)

目录号: HY-P75180
产品使用指南

GAD1/GAD67 蛋白利用吡哆醛 5'-磷酸作为辅助因子,并在抑制性神经递质 γ-氨基丁酸 (GABA) 的合成中充当催化剂。GAD1 在谷氨酸转化为 GABA 的过程中发挥着关键作用,GABA 是一种参与调节神经元兴奋性的关键神经递质。GAD1/GAD67 蛋白, Human (sf9, His) 是重组的 GAD1/GAD67 蛋白,由 Sf9 insect cells 表达,带有 C-His 标签。GAD1/GAD67 蛋白, Human (sf9, His) 全长 594 个氨基酸,分子量约为 ~64 kDa。

MCE 的所有产品仅用作科学研究或药证申报,我们不为任何个人用途提供产品和服务

重组蛋白定制服务

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
50 μg   询价  
100 μg   询价  

* Please select Quantity before adding items.

  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The GAD1/GAD67 protein utilizes pyridoxal 5'-phosphate as a cofactor and acts as a catalyst in the synthesis of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). GAD1 plays a key role in the conversion of glutamate to GABA, a key neurotransmitter involved in regulating neuronal excitability. GAD1/GAD67 Protein, Human (sf9, His) is the recombinant human-derived GAD1/GAD67 protein, expressed by Sf9 insect cells , with C-His labeled tag. The total length of GAD1/GAD67 Protein, Human (sf9, His) is 594 a.a., with molecular weight of ~64 kDa.

研究背景

谷氨酸脱羧酶 1 (GAD1),也称为 GAD67,是一种通过催化抑制性神经递质 γ-氨基丁酸 (GABA) 的合成在神经传递中发挥关键作用的酶。GAD1 利用吡哆醛 5'-磷酸作为谷氨酸脱羧形成 GABA 的辅助因子,GABA 是调节中枢神经系统神经元兴奋性的重要神经递质。GAD1 平衡产生 GABA 对于维持神经回路的抑制-兴奋平衡至关重要,并且与神经系统的各种生理和病理状况有关。

种属

Human

表达系统

Sf9 insect cells

标签

C-His

蛋白编号

Q99259 (M1-L594)

基因 ID
蛋白结构
N-term
GAD1 (M1-L594)
Accession # Q99259
His
C-term
同用名
Glutamate decarboxylase 1; GAD-67; GAD1; GAD
分子量

Approximately 64 kDa

纯度

Greater than 80% as determined by reducing SDS-PAGE

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

GAD1/GAD67 Protein, Human (sf9, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

您最近查看的产品:

Your information is safe with us. * Required Fields.

   产品名称:

 

* 需求量:

* 客户姓名:

 

* Email:

* 电话:

 

* 公司或机构名称:

   留言给我们:

Bulk Inquiry

Inquiry Information

产品名称:
GAD1/GAD67 Protein, Human (sf9, His)
目录号:
HY-P75180
需求量: