GDNF 蛋白, Human (134a.a, HEK293)

GDNF Protein, Human (134a.a, HEK293) is the recombinant human-derived GDNF protein, expressed by HEK293, with tag free tag.

GDNF 是一种神经营养因子，能够增强多巴胺能神经元的存活和形态分化，并提高其高亲和力多巴胺摄取。其作用机制是通过与核心受体 GFRA1 结合，进而导致 RET 受体的自磷酸化和激活。此外，GDNF 还参与神经嵴的发育过程。by similar: 该功能描述基于多个研究数据支持。

Human

HEK293

Tag Free

P39905-1 (S78-I211)

2668

Full Length of GDNF

Approximately 15-22 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years from date of receipt. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Lyophilized powder.