Glucose-6-phosphate isomerase 蛋白, Mouse (P.pastoris, His)

Glucose-6-phosphate isomerase protein exists in the cytoplasm and has dual functions. It converts glucose-6-phosphate into fructose-6-phosphate, playing a vital role in glycolysis and gluconeogenesis. Glucose-6-phosphate isomerase Protein, Mouse (P.pastoris, His) is the recombinant mouse-derived Glucose-6-phosphate isomerase protein, expressed by P. pastoris , with N-6*His labeled tag. The total length of Glucose-6-phosphate isomerase Protein, Mouse (P.pastoris, His) is 557 a.a., with molecular weight of ~64.6 kDa.

6-磷酸葡萄糖异构酶蛋白位于细胞质中，具有双重功能：催化6-磷酸葡萄糖转化为6-磷酸果糖，在糖异生过程中的糖酵解和逆反应中发挥关键作用。除了参与代谢途径的酶促作用外，这种蛋白质还表现出作为分泌细胞因子的额外作用。作为血管生成因子 (AMF)，它可刺激内皮细胞运动，表明其参与血管生成。此外，葡萄糖-6-磷酸异构酶充当神经营养因子，称为神经白介素，特别影响脊髓和感觉神经元。值得注意的是，它是由凝集素刺激的 T 细胞分泌的，可诱导免疫球蛋白分泌。这种多方面的蛋白质展示了其多功能性，既有助于基本代谢过程，又表现出细胞外功能，对血管生成、神经营养支持和免疫反应有影响。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Mouse

P. pastoris

N-6*His

P06745 (2A-558E)

14751  [NCBI]

AALTRNPQFQKLLEWHRANSANLKLRELFEADPERFNNFSLNLNTNHGHILVDYSKNLVNKEVMQMLVELAKSRGVEAARDNMFSGSKINYTENRAVLHVALRNRSNTPIKVDGKDVMPEVNRVLDKMKSFCQRVRSGDWKGYTGKSITDIINIGIGGSDLGPLMVTEALKPYSKGGPRVWFVSNIDGTHIAKTLASLSPETSLFIIASKTFTTQETITNAETAKEWFLEAAKDPSAVAKHFVALSTNTAKVKEFGIDPQNMFEFWDWVGGRYSLWSAIGLSIALHVGFDHFEQLLSGAHWMDQHFLKTPLEKNAPVLLALLGIWYINCYGCETHALLPYDQYMHRFAAYFQQGDMESNGKYITKSGARVDHQTGPIVWGEPGTNGQHAFYQLIHQGTKMIPCDFLIPVQTQHPIRKGLHHKILLANFLAQTEALMKGKLPEEARKELQAAGKSPEDLEKLLPHKVFEGNRPTNSIVFTKLTPFILGALIAMYEHKIFVQGIMWDINSFDQWGVELGKQLAKKIEPELEGSSAVTSHDSSTNGLISFIKQQRDTKLE

Approximately 64.6 kDa

Greater than 90% as determined by reducing SDS-PAGE.

无菌粉末.

Lyophilized after extensive dialysis against solution in PBS, 6% Trehalose, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.