1. 重组蛋白
  2. Receptor Proteins
  3. IGFLR1 蛋白, Human (HEK293, C-His)

IGFLR1 蛋白, Human (HEK293, C-His)

目录号: HY-P700454
产品使用指南

IGFLR1 蛋白是一种可能的细胞膜受体,对 IGF 样家族蛋白 IGFL1 和 IGFL3 表现出特异性亲和力,与其他蛋白相比具有更高的结合亲和力。这种选择性相互作用表明 IGFLR1 在介导细胞对这些配体的反应中发挥着关键作用,强调了它在复杂的细胞信号通路网络中的重要性。IGFLR1 蛋白, Human (HEK293, C-His) 是重组的 IGFLR1 蛋白,由 HEK293 表达,带有 C-6*His 标签。IGFLR1 蛋白, Human (HEK293, C-His) 全长 141 个氨基酸,分子量为 17.4 kDa。

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描述

IGFLR1 protein, a probable cell membrane receptor, exhibits specific affinity for IGF-like family proteins IGFL1 and IGFL3, with higher binding affinity compared to others. This selective interaction profile suggests a key role for IGFLR1 in mediating cellular responses to these ligands, emphasizing its significance in the intricate network of cellular signaling pathways. IGFLR1 Protein, Human (HEK293, C-His) is the recombinant human-derived IGFLR1 protein, expressed by HEK293, with C-6*His labeled tag. The total length of IGFLR1 Protein, Human (HEK293, C-His) is 141 a.a., with molecular weight of 17.4 kDa.

研究背景

IGFLR1 蛋白可能是 IGF 样家族蛋白的细胞膜受体,表现出对 IGFL1 和 IGFL3 的特异性亲和力,与其他家族成员相比具有更高的结合亲和力。这表明 IGFLR1 和这些配体之间存在选择性相互作用。此外,IGFLR1 还可能表现出结合 IGFL2 的能力,进一步扩展其潜在的配体库。独特的结合偏好强调了受体在介导细胞对 IGF 样家族蛋白的反应中的作用,强调了它在复杂的细胞信号通路网络中的重要性。

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

Q9H665 (S23-P163)

基因 ID
蛋白结构
N-term
IGFLR1 (S23-P163)
Accession # Q9H665
6*His
C-term
同用名
IGFLR1; IGF-like family receptor 1; TMEM149, transmembrane protein 149 , U2(RNU2) small nuclear RNA auxiliary factor 1 like 4 , U2AF1L4; FLJ22573; transmembrane protein 149; U2 small nuclear RNA auxiliary factor 1-like 4; U2(RNU2) small nuclear RNA auxiliary factor 1-like 4; TMEM149; U2AF1L4;
氨基酸序列

SQYCGRLEYWNPDNKCCSSCLQRFGPPPCPDYEFRENCGLNDHGDFVTPPFRKCSSGQCNPDGAELCSPCGGGAVTPTPAAGGGRTPWRCRERPVPAKGHCPLTPGNPGAPSSQERSSPASSIAWRTPEPVPQQAWPNFLP

分子量

17.4 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

IGFLR1 Protein, Human (HEK293, C-His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
IGFLR1 Protein, Human (HEK293, C-His)
目录号:
HY-P700454
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