IL-7 蛋白, Mouse

IL-7 protein regulates lymphocyte population and maintains lymphoid homeostasis by developing, expanding, and supporting survival of T-cells and B-cells. It interacts with IL7R and CSF2RG receptors to exert its effects. IL-7 Protein, Mouse is the recombinant mouse-derived IL-7 protein, expressed by E. coli , with tag free. The total length of IL-7 Protein, Mouse is 129 a.a., with molecular weight of ~18 kDa.

IL-7蛋白是一种造血细胞因子，在幼稚和记忆T细胞和B细胞的发育、扩增和存活中发挥着至关重要的作用，从而调节成熟淋巴细胞的数量并维持淋巴稳态。它与IL7R和CSF2RG受体相互作用而发挥作用。

1.Measured in a cell proliferation assay using antibody against CD3-activated human peripheral blood lymphocytes (PBL) and the ED₅₀ is typically 0.4-5.2 ng/mL.
2.Measured in a cell proliferation assay using antibody against CD3-activated human peripheral blood mononuclear cell (PBMC). The ED₅₀ for this effect is typically 0.4-4 ng/mL.

Mouse

E. coli

Tag Free

Q544C8 (E26-I154)

16196  [NCBI]

Approximately 18 kDa

Greater than 90% as determined by reducing SDS-PAGE

无菌粉末.

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O.

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.