MST4/STK26 蛋白, Human (sf9, GST)

MST4/STK26 is a kinase that mediates cell growth, regulates apoptosis, and, together with STK24, is involved in negatively affecting Golgi reorientation during RHO-triggered polarized cell migration. MST4/STK26 enhances autophagic flux by phosphorylating ATG4B at 'Ser-383'. MST4/STK26 Protein, Human (sf9, GST) is the recombinant human-derived MST4/STK26 protein, expressed by Sf9 insect cells , with GST labeled tag. The total length of MST4/STK26 Protein, Human (sf9, GST) is 416 a.a., with molecular weight of ~65 kDa.

MST4/STK26 是一种丝氨酸/苏氨酸蛋白激酶，作为细胞生长的介质，并在细胞凋亡中发挥调节作用。它与 STK24 一起参与 RHO 激活触发的极化细胞迁移过程中高尔基体重新定向的负调节。此外，MST4/STK26 在“Ser-383”位点磷酸化 ATG4B，从而增强自噬通量。这些活动强调了它参与多种细胞过程，包括生长调节、细胞凋亡调节以及通过高尔基体重新定向和自噬调节来协调细胞迁移。

The specific activity was determined to be 15 nmol/min/mg using MBP as substrate.

Human

Sf9 insect cells

GST

Q9P289-1 (M1-P416)

51765  [NCBI]

Approximately 65 kDa

Greater than 95% as determined by reducing SDS-PAGE.

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM PB, 300 mM NaCl, pH 7.0, 25% glycerol, 0.5 mM TCEP, 0.5 mM EDTA, 0.5 mM GSH.

<1 EU/μg, determined by LAL method.

Please use rapid thawing with running water to thaw the protein.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.