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  3. NPR1/NPRA 蛋白, Cynomolgus (HEK293, mFc)

NPR1/NPRA 蛋白, Cynomolgus (HEK293, mFc)

目录号: HY-P703701
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NPR1/NPRA 蛋白, Cynomolgus (HEK293, mFc) 是重组食蟹猴来源的 NPR1/NPRA 蛋白,由 HEK293 表达,带有 C-mFc 标签。

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描述

NPR1/NPRA Protein, Cynomolgus (HEK293, mFc) is the recombinant cynomolgus-derived NPR1/NPRA protein, expressed by HEK293, with C-mFc tag.

研究背景

NPR1/NPRA 是心房钠尿肽 NPPA/ANP 和脑钠尿肽 NPPB/BNP 的受体,这些肽是强效的血管活性激素,在心血管稳态中起关键作用。它在调节内皮细胞衰老和血管老化中发挥重要作用。当被 ANP 或 BNP 激活时,NPR1/NPRA 会刺激环磷酸鸟苷 (cGMP) 的产生,通过激活蛋白激酶 cGMP 依赖性 1/PRKG1 和随后的 PRKAA1 促进血管张力和容量稳态,从而控制血压并维持心血管稳态。

种属

Cynomolgus

表达系统

HEK293

标签

C-mFc

蛋白编号

XP_005541810 (G33-E473)

蛋白长度

Partial

中文名
NPR1 蛋白/NPRA 蛋白
预测分子量
74.6 kDa
分子量

Approximately 80-110 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

纯度

Greater than 95% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

NPR1/NPRA Protein, Cynomolgus (HEK293, mFc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
NPR1/NPRA Protein, Cynomolgus (HEK293, mFc)
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HY-P703701
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