1. 重组蛋白
  2. CD Antigens Receptor Proteins
  3. T Cell CD Proteins NK Cell CD Proteins Pattern Recognition Receptors
  4. C-type Lectin Receptors
  5. CD161/KLRB1
  6. OCIL/CLEC2D 蛋白, Rat (HEK293, Fc)

OCIL/CLEC2D 蛋白, Rat (HEK293, Fc)

目录号: HY-P76831
COA 产品使用指南

OCIL/CLEC2D 蛋白,也称为破骨细胞抑制性凝集素 (OCIL) 或 C 型凝集素结构域家族 2 成员 D (CLEC2D),作为位于细胞表面的凝集素型受体发挥作用。凝集素是特异性结合碳水化合物的蛋白质,OCIL/CLEC2D 通过充当凝集素型受体参与碳水化合物识别和信号传导过程。OCIL/CLEC2D 蛋白, Rat (HEK293, Fc) 是重组的 OCIL/CLEC2D 蛋白,由 HEK293 表达,带有 N-hFc 标签。OCIL/CLEC2D 蛋白, Rat (HEK293, Fc) 全长 136 个氨基酸,分子量分别为 44-54 & 36 kDa。

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  • 生物活性

  • 技术参数

  • 产品性质

  • 产品资料

描述

The OCIL/CLEC2D protein, also known as osteoclast inhibitory lectin (OCIL) or C-type lectin domain family 2 member D (CLEC2D), functions as a lectin-type receptor located on the cell surface. Lectins are proteins that specifically bind to carbohydrates, and OCIL/CLEC2D is involved in carbohydrate recognition and signaling processes by acting as a lectin-type receptor. OCIL/CLEC2D Protein, Rat (HEK293, Fc) is the recombinant rat-derived OCIL/CLEC2D protein, expressed by HEK293 , with N-hFc labeled tag. The total length of OCIL/CLEC2D Protein, Rat (HEK293, Fc) is 136 a.a., with molecular weight of 44-54 & 36 kDa, respectively.

研究背景

OCIL/CLEC2D 蛋白,也称为破骨细胞抑制性凝集素 (OCIL) 或 C 型凝集素结构域家族 2 成员 D (CLEC2D),作为位于细胞表面的凝集素型受体发挥作用。凝集素是与碳水化合物特异性结合的蛋白质,通过作为凝集素型受体,OCIL/CLEC2D 参与碳水化合物识别和信号传导过程。OCIL/CLEC2D 蛋白的确切作用和功能在给定的参考通道中没有具体说明,但根据其作为凝集素型受体的分类,它可能通过识别特定的蛋白参与介导细胞相互作用、粘附或免疫反应。碳水化合物分子。需要进一步研究以充分了解 OCIL/CLEC2D 蛋白的生物学意义和分子机制。

生物活性

Measured by its binding ability in a functional ELISA. Immobilized Human CD161, at 10μg/mL (100 μL/well) can bind Rat OCIL. The ED50 for this effect is 3.446 μg/mL.

种属

Rat

表达系统

HEK293

标签

N-hFc

蛋白编号

Q925N7 (K98-L233)

基因 ID

113937  [NCBI]

蛋白结构
N-term
hFc
OCIL (K98-L233)
Accession # Q925N7
C-term
同用名
C-type lectin domain family 2 member D5; Osteoclast inhibitory lectin; Ocil; Clec2d5
氨基酸序列

KKTAQISTINTYAACPRNWIGVGNKCFYFNEIPSNWTLSQTLCKEQGAELARFDTEEELNFLRRYKGSSGYWFGLHRESSAHPWKWTDNTEYNNSVSIGGDEKHGFLSDNGFSSGRGYIVRKSICRKPNSYTSQCL

分子量

Approximately 43-55 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE

性状

无菌粉末

组分

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US; may vary elsewhere.

文件资料
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
OCIL/CLEC2D Protein, Rat (HEK293, Fc)
目录号:
HY-P76831
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