PAEP 蛋白, Human (HEK293, His)

PAEP protein is a glycoprotein that regulates fertilization steps and exhibits immunomodulatory effects. PAEP Protein, Human (HEK293, His) is the recombinant human-derived PAEP protein, expressed by HEK293 , with N-10*His labeled tag. The total length of PAEP Protein, Human (HEK293, His) is 162 a.a., with molecular weight of ~18.06 kDa.

PAEP 蛋白是一种糖蛋白，复杂地调节受精过程中的关键步骤，同时还发挥免疫调节作用。在生殖组织中，已鉴定出四种不同的糖型，即糖蛋白-S、-A、-F 和 -C，每种糖型都具有独特的糖基化模式和生物活性。例如，Glycodelin-A 具有避孕和免疫抑制活性。另一方面，Glycodelin-C 在刺激精子与透明带的结合方面发挥作用。相反，Glycodelin-F 可抑制精子与透明带的结合，并显着抑制孕酮诱导的精子顶体反应。此外，精浆中存在的 Glycodelin-S 可以维持人类精子的无能力状态。该蛋白质形成同二聚体，进一步强调其在协调受精过程中的关键事件和调节免疫反应方面的结构复杂性和功能多样性。

Data is not available.

Human

HEK293

N-10*His

P09466 (M19-F180)

5047  [NCBI]

MDIPQTKQDLELPKLAGTWHSMAMATNNISLMATLKAPLRVHITSLLPTPEDNLEIVLHRWENNSCVEKKVLGEKTENPKKFKINYTVANEATLLDTDYDNFLFLCLQDTTTPIQSMMCQYLARVLVEDDEIMQGFIRAFRPLPRHLWYLLDLKQMEEPCRF

Approximately 18.06 kDa

• 
  Greater than 95% as determined by reducing SDS-PAGE

溶液.

Supplied as a 0.2 μm filtered solution of 20 mM Tris-HCl, 150 mM NaCl, 30% glycerin, pH 8.0.

<1 EU/μg, determined by LAL method.

N/A.

Stored at -80°C for 1 year. It is stable at -20°C for 3 months after opening. It is recommended to freeze aliquots at -80°C for extended storage. Avoid repeated freeze-thaw cycles.

Shipping with dry ice.