PRDX5/Peroxiredoxin-5 蛋白, Mouse (His)

The PRDX5/Peroxiredoxin-5 protein is a thiol-specific peroxidase that reduces hydrogen peroxide and organic hydroperoxides to water and alcohols. It plays a vital role in cellular protection from oxidative stress and detoxifying peroxides to maintain redox balance. PRDX5/Peroxiredoxin-5 Protein, Mouse (His) is the recombinant mouse-derived PRDX5/Peroxiredoxin-5 protein, expressed by E. coli , with N-His labeled tag. The total length of PRDX5/Peroxiredoxin-5 Protein, Mouse (His) is 162 a.a., with molecular weight of ~18.5 kDa.

PRDX5/Peroxiredoxin-5 蛋白作为硫醇特异性过氧化物酶发挥作用，分别催化过氧化氢和有机氢过氧化物还原为水和醇。这种蛋白质通过解毒各种过氧化物，在细胞保护免受氧化应激方面发挥着至关重要的作用，显示出其在维持细胞氧化还原平衡方面的重要性。此外，PRDX5 作为过氧化氢介导的信号事件的传感器，表明它参与调节细胞对氧化应激的反应。PRDX5 的双重功能强调了其在细胞防御机制中的重要性及其对氧化还原信号传导相关调节途径的潜在贡献。

The enzyme activity of this recombinant protein is testing in progress, we cannot offer a guarantee yet.

Mouse

E. coli

N-His

P99029 (M49-L210)

54683  [NCBI]

MAPIKVGDAIPSVEVFEGEPGKKVNLAELFKGKKGVLFGVPGAFTPGCSKTHLPGFVEQAGALKAKGAQVVACLSVNDVFVIEEWGRAHQAEGKVRLLADPTGAFGKATDLLLDDSLVSLFGNRRLKRFSMVIDNGIVKALNVEPDGTGLTCSLAPNILSQL

Approximately 18.5 kDa

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  Greater than 95% as determined by reducing SDS-PAGE.

无菌粉末

Lyophilized from a 0.2 μm filtered solution of 20 mM PB, 150 mM NaCl, pH 7.4.

<1 EU/μg, determined by LAL method.

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH₂O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Room temperature in continental US; may vary elsewhere.