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  3. PSCA 蛋白, Human (HEK293, His)

PSCA 蛋白, Human (HEK293, His)

目录号: HY-P704318
产品使用指南 技术支持

PSCA蛋白在细胞增殖中发挥调节作用,在体外已显示出对细胞增殖的抑制作用。此外,PSCA 可能作为烟碱乙酰胆碱受体 (nAChR) 活性的调节剂,在体外特异性抑制尼古丁诱导的信号传导,可能影响含有 α-3:β-2 或 α-7 的 nAChR。PSCA 蛋白, Human (HEK293, His) 是重组的 PSCA 蛋白,由 HEK293 表达,带有 C-His 标签。

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描述

PSCA protein plays a role in the regulation of cell proliferation and has shown an inhibitory effect on cell proliferation in vitro. In addition, PSCA may act as a modulator of nicotinic acetylcholine receptor (nAChR) activity, specifically inhibiting nicotine-induced signaling in vitro, possibly affecting α-3:β-2 or α-7-containing nAChRs. PSCA Protein, Human (HEK293, His) is the recombinant human-derived PSCA protein, expressed by HEK293, with C-His labeled tag.

研究背景

PSCA 蛋白似乎在细胞增殖调节中发挥作用,在体外表现出细胞增殖抑制活性。此外,PSCA 可以作为烟碱乙酰胆碱受体 (nAChR) 活性的调节剂,特别是在体外,它抑制尼古丁诱导的信号传导,可能涉及含有 α-3:β-2 或 α-7 的 nAChR。这种双重功能表明 PSCA 参与与增殖控制和烟碱乙酰胆碱受体活性调节相关的细胞过程,强调了其在细胞生理学和信号传导途径中的潜在重要性。

种属

Human

表达系统

HEK293

标签

C-His

蛋白编号

O43653 (L12-S86)

基因 ID

8000

蛋白结构
N-term
PSCA (L12-S86)
Accession # O43653
His
C-term
蛋白长度

Partial

同用名
PSCA; UNQ206; PRO232
预测分子量
10.4 kDa
分子量

Approximately 17-25 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.

糖基化修饰
Yes
纯度

Greater than 90% as determined by reducing SDS-PAGE.

内毒素含量

<1 EU/μg, determined by LAL method.

文件资料

PSCA Protein, Human (HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
PSCA Protein, Human (HEK293, His)
目录号:
HY-P704318
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