2. 重组蛋白
  3. Receptor Proteins Biotinylated Proteins
  4. PTK7 蛋白, Mouse (Biotinylated, HEK293, His, Avi)

PTK7 蛋白, Mouse (Biotinylated, HEK293, His, Avi)

目录号: HY-P703966
产品使用指南 技术支持

Ptk7蛋白是一种细胞表面受体，在调节细胞迁移和组织发育中发挥着至关重要的作用。Ptk7 蛋白的失调与多种疾病有关，包括癌症和发育障碍。靶向 Ptk7 蛋白可能通过调节细胞迁移、抑制肿瘤生长和促进正常组织发育来为这些疾病提供潜在的治疗干预。PTK7 蛋白, Mouse (Biotinylated, HEK293, His, Avi) 是重组的 PTK7 蛋白，由 HEK293 表达，带有 C-Avi 和 C-His 标签。

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SPR 检测服务   重组蛋白定制服务

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2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
50 μg   询价  
100 μg   询价  

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描述

Ptk7 Protein is a cell surface receptor that plays a crucial role in regulating cell migration and tissue development. Dysregulation of Ptk7 Protein has been associated with various diseases, including cancer and developmental disorders. Targeting Ptk7 Protein may offer potential therapeutic interventions in these conditions by modulating cell migration, inhibiting tumor growth, and promoting normal tissue development. PTK7 Protein, Mouse (Biotinylated, HEK293, His, Avi) is the recombinant mouse-derived PTK7 protein, expressed by HEK293, with C-Avi and C-His labeled tag.
研究背景

Ptk7 蛋白是一种无活性的酪氨酸激酶，在 Wnt 信号通路中发挥着至关重要的作用，特别是在非规范（Wnt/平面细胞极性信号传导）和规范 Wnt 信号通路中。它参与多种细胞过程，包括细胞粘附、迁移、极性、增殖、肌动蛋白细胞骨架重组和凋亡。Ptk7 蛋白还有助于胚胎发生、上皮组织组织和血管生成。此外，它还与 CTNNB1 相互作用，进一步凸显了它在 Wnt 信号传导中的重要性。
种属

Mouse
表达系统

HEK293
标签

C-Avi;C-8*His
蛋白编号

Q8BKG3 (A23-T696)
基因 ID

71461
蛋白结构
N-term
PTK7 (A23-T696)
Accession # Q8BKG3
8*His-Avi
C-term
蛋白长度

Extracellular Domain
中文名
生物素化 PTK7 蛋白
同用名
CCK-4; PTK7
预测分子量
77.5 kDa
分子量

Approximately 90-110 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
纯度

Greater than 95% as determined by Tris-Bis PAGE.
内毒素含量

<1 EU/μg, determined by LAL method.
文件资料
产品使用指南 (1213 KB)

PTK7 Protein, Mouse (Biotinylated, HEK293, His, Avi) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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