1. 重组蛋白
  2. CAR-T related Proteins
  3. TROP-2
  4. TROP-2 蛋白, Human (187a.a, HEK293, His)

TROP-2 蛋白, Human (187a.a, HEK293, His)

目录号: HY-P70728
COA 产品使用指南

TROP-2 蛋白作为一种潜在的生长因子受体出现,意味着参与与生长和信号传导相关的细胞过程。作为一种假定的受体,TROP-2 可能在转导调节细胞生长和增殖的信号中发挥至关重要的作用。TROP-2 蛋白, Human (187a.a, HEK293, His) 是重组的 TROP-2 蛋白,由 HEK293 表达,带有 C-6*His 标签。TROP-2 蛋白, Human (187a.a, HEK293, His) 全长 187 个氨基酸,分子量为 28-40 kDa。

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规格 价格 是否有货 数量
10 μg ¥600 In-stock
50 μg ¥1800 In-stock
100 μg   询价  

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描述

The TROP-2 protein emerged as a potential growth factor receptor, implying involvement in cellular processes related to growth and signaling. As a putative receptor, TROP-2 may play a crucial role in transducing signals that regulate cell growth and proliferation. TROP-2 Protein, Human (187a.a, HEK293, His) is the recombinant human-derived TROP-2 protein, expressed by HEK293 , with C-6*His labeled tag. The total length of TROP-2 Protein, Human (187a.a, HEK293, His) is 187 a.a., with molecular weight of 28-40 kDa.

研究背景

TROP-2 蛋白作为一种潜在的生长因子受体出现,表明它参与与生长和信号传导相关的细胞过程。作为一种假定的受体,TROP-2 可能在调节细胞生长、增殖和其他潜在细胞功能的信号转导中发挥至关重要的作用。与 TROP-2 介导的生长因子信号传导相关的特定配体和下游途径仍有待进一步研究。揭示 TROP-2 在生长因子信号传导中的详细分子机制和功能意义将有助于全面了解其在细胞生理学中的作用,并可能为针对该受体的治疗干预开辟途径。

种属

Human

表达系统

HEK293

标签

C-6*His

蛋白编号

P09758 (T88-T274)

基因 ID
蛋白结构
N-term
TROP-2 (T88-T274)
Accession # P09758
6*His
C-term
同用名
Tumor-associated calcium signal transducer 2; Membrane component chromosome 1 surface marker 1; Cell surface glycoprotein Trop-2; TACSTD2; TROP2
氨基酸序列

TLVRPSEHALVDNDGLYDPDCDPEGRFKARQCNQTSVCWCVNSVGVRRTDKGDLSLRCDELVRTHHILIDLRHRPTAGAFNHSDLDAELRRLFRERYRLHPKFVAAVHYEQPTIQIELRQNTSQKAAGDVDIGDAAYYFERDIKGESLFQGRGGLDLRVRGEPLQVERTLIYYLDEIPPKFSMKRLT

分子量

28-40 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.2 μm filtered solution of PBS, 5%Trehalose, 2 mM EDTA, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O.

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US;may vary elsewhere.

文件资料

TROP-2 Protein, Human (187a.a, HEK293, His) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
TROP-2 Protein, Human (187a.a, HEK293, His)
目录号:
HY-P70728
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