1. Gene
  2. TACSTD2 - tumor associated calcium signal transducer 2 Gene

TACSTD2 - tumor associated calcium signal transducer 2 Gene

中文名称:肿瘤相关钙信号转导 2

种属: Homo sapiens

同用名: EGP1; GP50; M1S1; EGP-1; TROP2; GA7331; GA733-1

基因 ID: 4070 | 基因类型: protein coding

关于 TACSTD2

Cytogenetic location: 1p32.1 Genomic coordinates (GRCh38): 1:58,575,433-58,577,252 (from NCBI)

This gene has 1 transcript (splice variant), 194 orthologues, 1 paralogue and is associated with 3 phenotypes.

功能概要

这种无内含子的基因编码一种癌相关抗原。该抗原是一种转导钙信号的细胞表面受体。该基因的突变与凝胶状滴状角膜营养不良有关。[RefSeq 提供,2009 年 12 月]

This intronless gene encodes a carcinoma-associated antigen. This antigen is a cell surface receptor that transduces calcium signals. Mutations of this gene have been associated with gelatinous drop-like corneal dystrophy.[provided by RefSeq, Dec 2009]

TACSTD2 基因产物(1)

mRNA Protein Name
NM_002353.3 NP_002344.2 tumor-associated calcium signal transducer 2 precursor

TACSTD2 蛋白结构

Thyroglobulin_1

Thyroglobulin_1: Thyroglobulin type-1 repeat (73 - 145)

  • 0
  • 100
  • 200
  • 300
  • 323 a.a.
蛋白主名 其他名称

tumor-associated calcium signal transducer 2

40kD glycoprotein, identified by monoclonal antibody GA733

重组 TACSTD2 蛋白

目录号 产品名 蛋白编号 纯度
HY-P70457 TROP-2 Protein, Human (248a.a, HEK293, His) P09758 (H27-T274) ≥95%
HY-P70770 TROP-2 Protein, Human (HEK293, His-Avi) P09758 (H27-T274) ≥95%
HY-P70728 TROP-2 Protein, Human (187a.a, HEK293, His) P09758 (T88-T274) ≥95%
HY-P71095 TROP-2 Protein, Human (187a.a, HEK293, Fc) P09758 (T88-T274) ≥95%
HY-P72015 TROP-2 Protein, Human (248a.a, HEK293, hFc) P09758 (H27-T274) ≥95%
HY-P74490 TROP-2 Protein, Human (HEK293, His-hFc) P09758 (H27-T274) ≥95%
HY-P78223 TROP-2 Protein, Human (Biotinylated, HEK293, His-Avi) P09758 (H27-T274) ≥95%
HY-P78539 TROP-2 Protein, Human (FITC, HEK293, His) P09758 (H27-T274) ≥95%

关联疾病

疾病名称 别名
Corneal Dystrophy, Gelatinous Drop-Like

Gelatinous Drop-Like Corneal Dystrophy

GDLD

Cdgdl

Corneal Amyloidosis

Lattice Corneal Dystrophy Type Iii

Amyloidosis, Corneal

Amyloid Corneal Dystrophy, Japanese Type

Gdcd

Primary Familial Amyloidosis Of The Cornea

Subepithelial Amyloidosis Of The Cornea

Corneal Dystrophy, Lattice Type 3

Corneal Dystrophy, Lattice Type Iii

Lattice Corneal Dystrophy, Type Iii

Amyloidosis Corneal

Lattice Corneal Dystrophy Type3

Amyloid Corneal Dystrophy Japanese Type

Dystrophy, Corneal, Gelatinous Drop-Like

Amyloid Of Cornea

Lattice Corneal Dystrophy

Familial Amyloid Neuropathy, Finnish Type

Familial Amyloid Polyneuropathy, Type V

Corneal Dystrophy
Epithelial And Subepithelial Dystrophy
Taeniasis

Beef Tapeworm Infection

Infection By Taeniarhynchus Saginatus

Taenia Saginata Infectious Disease

Taenia Saginata Infection

Pork Tapeworm Infection

Armed Tapeworm Infection

Infection By Taenia Solium

Intestinal Taenia Solium Infection

Pork Tapeworm

Taenia Solium Taeniasis

Adult Pork Tapeworm Infection

Adult Pork Tapeworm

Beef Tapeworm

Infection By Taenia Saginata

Unarmed Tapeworm Infection

Taenia Saginata Taeniasis

Infection Due To Adult Tapeworm Taenia Saginata

Mediocanellata Taenia Infection

Infestation By Taenia Saginata

Infestation By Taenia Mediocanellata

Gastrointestinal Carcinoma

Gastrointestinal Neoplasms

Coenurosis

Coenuriasis

Ovary Leiomyosarcoma

Leiomyosarcoma Of Ovary

Corneal Dystrophy, Reis-Bucklers Type

Reis-Bucklers Corneal Dystrophy

Rbcd

CDRB

Cdb1

Corneal Dystrophy Of Bowman Layer Type I

Geographic Corneal Dystrophy

Granular Corneal Dystrophy Type Iii

Reis-Bucklers' Corneal Dystrophy

Anterior Limiting Membrane Dystrophy Type I

Corneal Dystrophy Of Bowman Layer Type 1

Corneal Dystrophy Of Bowman Layer, Type I

Corneal Dystrophy, Geographic

Granular Corneal Dystrophy, Type Iii

Corneal Dystrophy Reis Bucklers Type

Corneal Dystrophy Geographic

Reis Bucklers Corneal Dystrophy

Reis Bucklers Dystrophy

Anterior Limiting Membrane Dystrophy Type 1

Atypical Granular Corneal Dystrophy

Granular Corneal Dystrophy Type 3

Superficial Granular Corneal Dystrophy

Corneal Dystrophy Of Bowman Layer, Type 1

Dystrophy, Corneal, Reis-Bucklers Type

Corneal Dystrophy, Thiel-Behnke Type

Thiel-Behnke Corneal Dystrophy

Tbcd

CDTB

Cdb2

Corneal Dystrophy Of Bowman Layer Type Ii

Anterior Limiting Membrane Dystrophy Type Ii

Waardenburg-Jonker Corneal Dystrophy

Corneal Dystrophy Of Bowman Layer, Type Ii

Corneal Dystrophy, Honeycomb-Shaped

Corneal Dystrophy Honeycomb-Shaped

Corneal Dystrophy Thiel Behnke Type

Corneal Dystrophy Honeycomb Shaped

Corneal Dystrophy Of The Bowman Layer Type 2

Thiel Behnke Corneal Dystrophy

Anterior Limiting Membrane Dystrophy Type 2

Corneal Dystrophy Of Bowman Layer Type 2

Curly Fiber Corneal Dystrophy

Honeycomb Corneal Dystrophy

Honeycomb-Shaped Corneal Dystrophy

Dystrophy, Corneal, Thiel-Behnke Type

Cysticercosis

Neurocysticercosis

Submacular Cysticercosis

Intestinal Taenia Solium Infection

Pork Tapeworm Infection

Tapeworm Infection: Intestinal Taenia Solum

Tapeworm Infection: Pork

Tenia Solium Infectious Disease

Taeniasis

Tenia Solium Infection

Cysticerciasis Infection Due To Larval Form Of Taenia Solium

Ovarian Carcinosarcoma

Ovarian Malignant Mixed Mullerian Tumor

Mmmt Of The Ovary

Malignant Mixed Mullerian Tumor Of The Ovary

Ovarian Malignant Mixed Epithelial Mesenchymal Tumor

Ovarian Malignant Mesodermal Mixed Tumor

Ovarian Mmmt

Malignant Mixed Müllerian Tumor Of The Ovary

Ovarian Malignant Mixed Müllerian Tumor

Carcinosarcoma Of Ovary

Corneal Deposit

Deposits - Cornea

Granular Corneal Dystrophy

Granular Dystrophy Corneal

Corneal Dystrophies, Hereditary

Hereditary Corneal Dystrophy

Corneal Dystrophy Nos

Familial Hereditary Corneal Degeneration

Hereditary Corneal Opacity

Corneal Dystrophy, Avellino Type

Avellino Corneal Dystrophy

CDA

Combined Granular-Lattice Corneal Dystrophy

Cgd2

Granular Corneal Dystrophy Type 2

Acd

Granular Corneal Dystrophy 2

Corneal Dystrophy Avellino Type

Granular Corneal Dystrophy Type Ii

Granular Corneal Dystrophy, Type Ii

Combined Granular-Lattice Corneal Dystrophies

Granular And Lattice Corneal Dystrophies

Granular-Lattice Corneal Dystrophy

Gcd2

Gcdii

Granular-Lattice Corneal Dystrophy

Macular Dystrophy, Corneal

Macular Corneal Dystrophy

MCD

Corneal Dystrophy, Macular Type

Groenouw Type Ii Corneal Dystrophy

Fehr Corneal Dystrophy

Macular Dystrophy, Corneal Type 1

Mcdc1

Macular Corneal Dystrophy Type Ii

Macular Corneal Dystrophy, Type Ii

Macular Corneal Dystrophy, Type I

Mcdc1, Formerly

Macular Dystrophy, Corneal, 1

Macular Corneal Dystrophy Type 1

Corneal Dystrophy Groenouw Type Ii

Corneal Dystrophy Macular Type

Macular Corneal Dystrophy Type I

Dystrophy, Macular, Corneal

Premature Ovarian Failure 18

POF18

Primary Ovarian Insufficiency 18

Ovarian Failure, Premature, Type 18

Corneal Dystrophy, Band-Shaped

Band Keratopathy

Band-Shaped Keratopathy

Corneal Degeneration

Degenerative Corneal Opacity

Klatskin'S Tumor

Klatskin Tumor

Hilar Cholangiocarcinoma

Perihilar Cholangiocarcinoma

Hilar Cholangiocellular Carcinoma

Klatskin Tumour

Klatskin'S Tumour

Perihilar Extrahepatic Bile Duct Carcinoma

Hilar Cca

Adenocarcinoma Of Hepatic Duct

Klatskin Tumour Of Biliary Tree

Ovarian Cancer

Ovarian Carcinoma

Ovarian Neoplasm

Malignant Tumour Of Ovary

Cancer Of The Ovary

Epithelial Ovarian Cancer

Neoplasm Of Ovary

Ovarian Neoplasms

Ovarian Cancers

Malignant Neoplasm Of Ovary

Primary Malignant Neoplasm Of Ovary

Ovarian Cancer, Somatic

Malignant Ovarian Tumor

Ovary Neoplasm

Primary Ovarian Cancer

Tumor Of The Ovary

Malignant Neoplasm Of The Ovary

Malignant Tumor Of The Ovary

Ovarian Malignant Tumor

OC

Ovarian Carcinomas

Cancer, Ovarian

Cancer Of Ovary

Ovary Cancer

Ca Ovary

Pancreatic Cancer

Pancreatic Carcinoma

Carcinoma Of Pancreas

Familial Pancreatic Carcinoma

Pancreatic Neoplasm

Pancreatic Carcinoma, Familial

Malignant Neoplasm Of Pancreas

Pancreatic Acinar Carcinoma

Pancreatic Tumor

Familial Pancreatic Cancer

Neoplasm Of The Pancreas

Cancer Of The Pancreas

Pancreatic Carcinoma, Somatic

Pancreatic Cancer, Somatic

Ca Body Of Pancreas

Ca Head Of Pancreas

Ca Tail Of Pancreas

Malignant Neoplasm Of Body Of Pancreas

Malignant Neoplasm Of Head Of Pancreas

Malignant Neoplasm Of Tail Of Pancreas

Pancreas Neoplasm

Exocrine Cancer

Exocrine Pancreas Carcinoma

Hereditary Pancreatic Cancer

Hereditary Pancreatic Carcinoma

PNCA

Pancreatic Cancer, Susceptibility To

Carcinoma Of Head Of Pancreas

Pancreatic Neoplasms

Pancreatic Tumors

Cancer, Pancreatic

Cancer Of Pancreas

Mixed Islet Cell With Exocrine Carcinoma Of Unspecified Site

Epithelial-Stromal Tgfbi Dystrophy
Corneal Disease

Corneal Diseases

Corneal Disorders

疾病名称 别名
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

直系同源

种属 基因名 来源 基因 ID
Bos taurus TACSTD2 VGNC VGNC:35563
Felis catus TACSTD2 VGNC VGNC:80372
Mus musculus TACSTD2 MGD MGI:1861606
Macaca mulatta TACSTD2 VGNC VGNC:78085
Rattus norvegicus TACSTD2 RGD RGD:1359498
Macaca fascicularis TACSTD2 NCBI
Others TACSTD2 NCBI