1. 重组蛋白
  2. Receptor Proteins
  3. TSLP R 蛋白, Human (HEK293, Fc)

TSLP R 蛋白, Human (HEK293, Fc)

目录号: HY-P70794
COA 产品使用指南

TSLP R 蛋白是 TSLP 的受体,与 IL7R 形成功能复合物,激活 STAT3STAT5 促进细胞增殖。它还激活 JAK2,帮助造血系统发育。TSLP R 与 CRLF2 和 IL7R 形成异二聚体,突显其在对细胞反应和造血发育至关重要的复杂信号通路中的作用。TSLP R 蛋白, Human (HEK293, Fc) 是重组的 TSLP R 蛋白,由 HEK293 表达,带有 C-hFc 标签。TSLP R 蛋白, Human (HEK293, Fc) 全长 207 个氨基酸,分子量为 60-80 kDa。

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规格 价格 是否有货 数量
10 μg ¥800 In-stock
50 μg ¥2400 In-stock
100 μg   询价  

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描述

TSLP R Protein, a receptor for TSLP, forms a functional complex with IL7R, activating STAT3 and STAT5 for cell proliferation. It also activates JAK2, aiding in hematopoietic system development. TSLP R forms a heterodimer with CRLF2 and IL7R, highlighting its role in intricate signaling pathways crucial for cellular responses and hematopoietic development. TSLP R Protein, Human (HEK293, Fc) is the recombinant human-derived TSLP R protein, expressed by HEK293 , with C-hFc labeled tag. The total length of TSLP R Protein, Human (HEK293, Fc) is 207 a.a., with molecular weight of 60-80 kDa.

研究背景

TSLP R 蛋白作为胸腺基质淋巴细胞生成素 (TSLP) 的受体,与 IL7R 结合形成功能复合物,能够通过激活 STAT3STAT5 刺激细胞增殖。此外,该受体激活 JAK2,有助于造血系统的发育。TSLP R 蛋白与 CRLF2 和 IL7R 形成异二聚体,表明其参与对细胞反应和造血发育至关重要的复杂信号通路。

种属

Human

表达系统

HEK293

标签

C-hFc

蛋白编号

Q9HC73 (G25-K231)

基因 ID
蛋白结构
N-term
TSLP R (G25-K231)
Accession # Q9HC73
hFc
C-term
同用名
CRL2; CRL2cytokine receptor CRL2 precusor; CRLF2; CRLF2Y; CRLM-2; Cytokine receptor-like 2; cytokine receptor-like factor 2; ILXR; IL-XR; P2RY8/CRLF2 fusion; PCOR1; TSLP R; TSLP receptor; TSLPR
氨基酸序列

GAAEGVQIQIIYFNLETVQVTWNASKYSRTNLTFHYRFNGDEAYDQCTNYLLQEGHTSGCLLDAEQRDDILYFSIRNGTHPVFTASRWMVYYLKPSSPKHVRFSWHQDAVTVTCSDLSYGDLLYEVQYRSPFDTEWQSKQENTCNVTIEGLDAEKCYSFWVRVKAMEDVYGPDTYPSDWSEVTCWQRGEIRDACAETPTPPKPKLSK

分子量

60-80 kDa

纯度

Greater than 95% as determined by reducing SDS-PAGE.

性状

无菌粉末.

组分

Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.

内毒素含量

<1 EU/μg, determined by LAL method.

复溶方法

It is not recommended to reconstitute to a concentration less than 100 μg/mL in ddH2O. For long term storage it is recommended to add a carrier protein (0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose).

保存条件 & 期限

Stored at -20°C for 2 years. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer (with carrier protein). It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

运输条件

Room temperature in continental US;may vary elsewhere.

文件资料

TSLP R Protein, Human (HEK293, Fc) 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • 复溶计算器

  • 重组蛋白稀释计算器

  • 比活力计算器

The reconstitution calculator equation

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration

Volume (to add to vial) = Mass (in vial) ÷ Desired Reconstitution Concentration
= ÷

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

The specific activity calculator equation

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)

Specific Activity (Unit/mg) = 106 ÷ Biological Activity (ED50)
Unit/mg = 106 ÷ ng/mL

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产品名称:
TSLP R Protein, Human (HEK293, Fc)
目录号:
HY-P70794
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