1. 一站式药筛
  2. 化合物库
  3. 生物活性化合物库系列
  4. 疾病相关化合物库
  5. 抗肿瘤化合物库
抗肿瘤化合物库 - Anti-Cancer Compound Library

Cat. No.: HY-L025

癌症是全球第二大死亡原因,严重威胁人类健康。肿瘤和恶性肿瘤是癌症的其他常见名称。细胞周期调控和细胞分裂过程失调是导致癌症发生的主要原因。靶向治疗通过靶向控制癌细胞生长、分裂和扩散的蛋白质,在癌症治疗中发挥着重要作用。近年来的研究主要集中在靶向肿瘤生存的关键蛋白、肿瘤干细胞、肿瘤微环境、肿瘤免疫学等方面。

MCE 收录了 7,746 种抗肿瘤化合物,主要靶向激酶、细胞周期调控的关键蛋白,肿瘤发生相关的信号通路等,是筛选抗肿瘤药物的有用工具。

我们将在明确您的产品用途后,向符合资质的客户通过定制合成服务的方式提供 MCE 抗肿瘤化合物库,我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中,7,567 个产品以 10 mM 浓度提供,158 个产品以 2 mM 浓度提供,21 个产品以 3 mg/mL 浓度提供。

溶液包装中,我们对于溶液状态稳定且溶解度不低于 10 mM 的产品,提供 10 mM 溶液;对于溶液状态稳定且溶解度介于 2~10 mM 的产品,我们提供 2 mM 溶液;对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品,我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Compound Screening Libraries

Top Publications Citing Use of MCE Products

MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 产品资料
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 7,746 bioactive anti-cancer compounds for high throughput screening (HTS) and high content screening (HCS).

•   Targets include kinases, cell cycle key components, tumorigenesis related signaling pathways, popular targets in epigenetic studies, and more.

•   A useful tool for the discovery of anti-cancer drugs.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   Detailed compound information with structure, IC50, and brief introduction.

•   Validated NMR and HPLC to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 7,746 anti-cancer compounds supplied as pre-dissolved Solutions or Solid
Solution: 7,567 compounds supplied in 10 mM solution, 158 compounds supplied in 2 mM solution, 21 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

化合物库组成

Composition

CDK (216)

EGFR (184)

PI3K (171)

NF-κB (143)

VEGFR (137)

HDAC (112)

Akt (106)

COX (97)

PARP (94)

mTOR (93)

STAT (90)

Ras (88)

HIV (87)

FLT3 (82)

FGFR (78)

JAK (77)

PDGFR (76)

HSP (71)

Wnt (65)

ERK (64)

MMP (63)

Src (61)

PKC (56)

c-Kit (55)

Raf (55)

PPAR (50)

Btk (43)

MEK (42)

AMPK (40)

GSK-3 (37)

FAK (33)

相关服务推荐
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  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式(固体或溶液)
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  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称:
    Anti-Cancer Compound Library
    目录号:
    HY-L025
    需求量: