2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 老药新用化合物库系列
  6. 儿童药物库
儿童药物库 - Children’s Drug Library

Cat. No.: HY-L104

儿童药短缺是一个普遍且紧迫的问题。各种因素阻碍了儿童药物的开发，包括有限的商业利益、缺乏适当的基础设施和开展儿科临床试验的能力、试验设计的困难、伦理担忧和许多其他问题。由于这些因素，未经许可和超说明书用药在儿童中很常见，这可能会导致安全问题。

MCE提供 671 种儿童药物，所有这些药物都已被批准用于儿童疾病治疗或在儿童疾病治疗中处于临床试验中。MCE儿童药物库是药物再利用发现新的儿童适应症的有效工具。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE 儿童药物库，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，651 个产品以 10 mM 浓度提供，12 个产品以 2 mM 浓度提供，8 个产品以 3 mg/mL 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液；对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品，我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情
  • 产品资料
  • 化合物库组成

活性描述 & 特点

Biological Activity

•   A unique collection of 671 approved and clinical children’s drugs for high throughput screening (HTS) and high content screening (HCS).

•   Can be used for drug repurposing to discover new children’s indications.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and brief introduction.

•   NMR and HPLC validated ensure high purity.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 671 Children’s Drug-related compounds supplied as pre-dissolved Solutions or Solid.
Solution: 651 compounds supplied in 10 mM solution, 12 compounds supplied in 2 mM solution, 8 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode.

Storage:

-80°C

Shipping:

Blue ice

化合物库组成

Composition

HIV (36)

COX (19)

HCV (16)

mAChR (12)

JAK (8)

HBV (7)

FGFR (6)

HSV (6)

PARP (6)

MEK (5)

MMP (5)

RSV (5)

SGLT (5)

Src (5)

Akt (4)

AMPK (4)

CFTR (4)

PKC (4)

STAT (4)

ERK (3)

FKBP (3)

HDAC (3)

NKCC (3)

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  •  特定化合物
  •  化合物数量
  •  产品排布图
  •  浓度
  •  形式（固体或溶液）
  •  YES
联系专家定制
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    Children’s Drug Library
    目录号：
    HY-L104
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