2. Metabolic Enzyme/Protease Membrane Transporter/Ion Channel
  3. Endogenous Metabolite ATP Synthase
  4. 3-Hydroxyisobutyric acid sodium

3-Hydroxyisobutyric acid sodium 是 L-缬氨酸和胸腺嘧啶代谢途径的中间产物，可在尿液中发现。3-Hydroxyisobutyric acid sodium 是内皮细胞脂肪酸转运和胰岛素抵抗的分泌介质。3-Hydroxyisobutyric acid sodium 也能抑制幼年大鼠大脑皮层能量代谢的关键酶。3-Hydroxyisobutyric acid sodium 的水平与 3 - 羟基异丁酸尿症、糖尿病和酮症酸中毒症等多种疾病密切相关。

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3-Hydroxyisobutyric acid sodium Chemical Structure

3-Hydroxyisobutyric acid sodium Chemical Structure

CAS No. : 1219589-99-7

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3-Hydroxyisobutyric acid sodium 的其他形式现货产品:

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3-Hydroxyisobutyric acid sodium 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

3-Hydroxyisobutyric acid sodium is an intermediate in the metabolic pathways of L-valine and thymine, and can be found in urine. 3-Hydroxyisobutyric acid sodium is a secreted mediator of endothelial cell fatty acid transport and insulin resistance. 3-Hydroxyisobutyric acid sodium can also inhibit key enzymes of energy metabolism in the cerebral cortex of young rats. The levels of 3-Hydroxyisobutyric acid sodium are closely related to various diseases such as 3-hydroxyisobutyric aciduria, diabetes, and ketoacidosis[1][2][3][4].

IC50 & Target[1]

Human Endogenous Metabolite

 

体外研究
(In Vitro)

3-Hydroxyisobutyric acid (0.1-1 mM) sodium 在大鼠大脑皮层匀浆中，显著抑制呼吸链复合物 I-III 活性，总肌酸激酶和线粒体肌酸激酶活性以及 Na+、K+-ATP 酶活性[2]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

3-Hydroxyisobutyric acid sodium 相关抗体:
分子量

126.09

Formula

C4H7NaO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

3-Hydroxyisobutyric acid sodium 相关分类

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Keywords:

3-Hydroxyisobutyric acid1219589-99-7Endogenous MetaboliteATP SynthaseEndogenous metabolitegluconeogenesisL-valinethymine3-hydroxyisobutyric aciduriadiabetesketoacidosisInhibitorinhibitorinhibit

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