2. Anti-infection
  3. Bacterial Fungal
  4. 5-Geranoxy-7-methoxycoumarin

5-Geranoxy-7-methoxycoumarin 是一种具有抗癌、抗真菌和抗菌活性的香豆素。5-Geranoxy-7-methoxycoumarin 诱导细胞凋亡(apoptosis)。

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5-Geranoxy-7-methoxycoumarin Chemical Structure

5-Geranoxy-7-methoxycoumarin Chemical Structure

CAS No. : 7380-39-4

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规格 价格 是否有货 数量
5 mg ￥2421
1 周
10 mg ￥3876
1 周
25 mg
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5-Geranoxy-7-methoxycoumarin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

5-Geranoxy-7-methoxycoumarin is a coumarin with anti-cancer, antifungal, and  antibacterial activities. 5-Geranoxy-7-methoxycoumarin induces cell apoptosis[1][2].

体外研究
(In Vitro)

5-Geranoxy-7-methoxycoumarin (12.5-200 µM; 24-72 hours) induces a significant inhibition of cell growth in a time-dependent manner in SW480 cells[1].
5-Geranoxy-7-methoxycoumarin (50 µM;48 hours) promotes DNA fragmentation and causes apoptosis through inhibition of the p38 MAPK signaling pathway in SW480 cells[1].
5-Geranoxy-7-methoxycoumarin (50 µM; 24-48 hours) increases the percentage of cells in the sub G1/G0 phase from 5.3% (in control cells) to 18% after 48 h incubation[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

5-Geranoxy-7-methoxycoumarin 相关抗体:

Cell Proliferation Assay[1]

Cell Line: SW480
Concentration: 0-20 μM
Incubation Time: 24, 48 and 72 hours
Result: Inhibited cell growth by 67% at 72 hours.

Apoptosis Analysis[1]

Cell Line: SW480 cells
Concentration: 50 μM
Incubation Time: 48 hours
Result: Induced cell apoptosis.

Cell Cycle Analysis[1]

Cell Line: SW480 cells
Concentration: 50 μM
Incubation Time: 48 hours
Result: Inhibited cell cycle progression in vitro.
分子量

328.40

Formula

C20H24O4
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

5-Geranoxy-7-methoxycoumarin 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

5-Geranoxy-7-methoxycoumarin7380-39-4BacterialFungalApoptosisDNA fragmentationantifungalbacterialInhibitorinhibitorinhibit

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