2. Apoptosis Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Apoptosis Reactive Oxygen Species Xanthine Oxidase
  4. 6-Formylpterin

6-Formylpterin 

目录号: HY-113978 纯度: ≥95.0%
COA 产品使用指南

摩尔计算器

6-Formylpterin 是 Xanthine Oxidase 的抑制剂。6-Formylpterin 诱导 HL-60 细胞内ROS 生成以及细胞凋亡 (apoptosis)。6-Formylpterin 抑制 PanC-1 细胞增殖。

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6-Formylpterin Chemical Structure

6-Formylpterin Chemical Structure

CAS No. : 712-30-1

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6-Formylpterin 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

6-Formylpterin is an inhibitor of Xanthine Oxidase. 6-Formylpterin induces intracellular ROS generation and apoptosis in HL-60 cells. 6-Formylpterin suppresses cell proliferation in PanC-1 cells[1].

体外研究
(In Vitro)

6-Formylpterin (2 mM) 在 HL-60 细胞中产生 ROS [1]。
6-Formylpterin (0.5, 1, and 2 mM, 3 小时) 增加HL-60 和 Jurkat 细胞中 2O2 含量，导致细胞凋亡[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

6-Formylpterin 相关抗体:

Apoptosis Analysis[1]

Cell Line: HL-60 cells, Jurkat cells
Concentration: 0.5, 1, and 2 mM
Incubation Time: 3 h
Result: Induced apoptosis in HL-60 cells[1].
Inhibited Fas-mediated apoptosis in Jurkat cells in 0.5 mM[1].
分子量

191.15

Formula

C7H5N5O2
CAS 号
性状

固体

颜色

Light yellow to brown

运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

-20°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

纯度 & 产品资料

纯度: ≥95.0%

COA (169 KB) HNMR (246 KB) MS (72 KB)

产品使用指南 (1538 KB)
参考文献

6-Formylpterin 相关分类

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  • Do most proteins show cross-species activity?

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Keywords:

6-Formylpterin712-30-1ApoptosisReactive Oxygen SpeciesXanthine OxidaseXOCell proliferationHL-60PanC-1Inhibitorinhibitorinhibit

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