1. GPCR/G Protein
  2. Oxytocin Receptor
  3. OT antagonist 1

OT antagonist 1 

目录号: HY-103650
产品使用指南

OT antagonist 1 (Compound 4) 是一种有效的选择性催产素 (Oxytocin) 拮抗剂,Ki 为 50 nM。

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OT antagonist 1 Chemical Structure

OT antagonist 1 Chemical Structure

CAS No. : 479080-38-1

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生物活性

OT antagonist 1 (Compound 4) is a potent, selective Oxytocin antagonist with a Ki of 50 nM.

IC50 & Target

Ki: 50 nM (Oxytocin)[1]

体外研究
(In Vitro)

Oxytocin (OT) is a nonapeptide hormone that acts on the OT receptor, a seven-transmembrane (7TM) (Gq-coupled) receptor. The OT receptor has no subtypes but is related to the vasopressin receptors V1A, V1B and V2. OT antagonists have therapeutic potential in a number of areas including pre-term labour: Benign Prostatic Hyperplasia and sexual dysfunction. As a result there is significant interest in the identification of potent, selective, orally bioavailable OT antagonists[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

390.44

Formula

C22H22N4O3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2

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产品名称:
OT antagonist 1
目录号:
HY-103650
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