1. Signaling Pathways
  2. Stem Cell/Wnt
  3. YAP


The transcriptional coactivator Yes-associated protein (YAP) is a major regulator of organ size and proliferation in vertebrates. As such, YAP can act as an oncogene in several tissue types if its activity is increased aberrantly. YAP enhances multiple processes known to be important for tumor progression and metastasis, including cellular proliferation, transformation, migration, and invasion.

YAP 相关产品 (5):

Cat. No. Product Name Effect Purity
  • HY-B0146
    Verteporfin Inhibitor 99.58%
    Verteporfin (CL 318952) 是一种用于光动力疗法的光敏剂,用于消除与年龄相关的黄斑变性等疾病相关的眼内异常血管。 Verteporfin 是一种 YAP 抑制剂,可破坏 YAP-TEAD 相互作用。Verteporfin 可以诱导细胞自噬 (autophagy)。
  • HY-111429
    YAP/TAZ inhibitor-1 Inhibitor 98.04%
    YAP/TAZ inhibitor-1 是一种 YAP/TAZ 抑制剂,IC50 <0.100 μΜ,详细信息请参考专利文献 WO2017058716A1 中的化合物 1。
  • HY-P1728A
    Super-TDU (1-31) TFA
    Super-TDU (1-31) 是 Super-TDU 的多肽片段。Super-TDU 为 YAP-TEADs 相互作用抑制剂,具有抗肿瘤活性。
  • HY-P1728
    Super-TDU 1-31
    Super-TDU (1-31) 是 Super-TDU 的多肽片段。Super-TDU 为 YAP-TEADs 相互作用抑制剂,具有抗肿瘤活性。
  • HY-P1727A
    Super-TDU (TFA) Antagonist
    Super-TDU TFA 是通过靶向 YAP-TEAD 相互作用,针对胃癌的一种特异性 YAP 拮抗剂疗法,。
Isoform Specific Products

Your Search Returned No Results.

Sorry. There is currently no product that acts on isoform together.

Please try each isoform separately.