1. Signaling Pathways
  2. Immunology/Inflammation
  3. Macrophage migration inhibitory factor (MIF)

Macrophage migration inhibitory factor (MIF) 

Macrophage migration inhibitory factor (MIF) is a proinflammatory cytokine encoded within a functionally polymorphic genetic locus. MIF is a highly conserved 12.5 kDa secretory protein that is involved in numerous biological processes. The expression and secretion profile of MIF suggests that MIF to be ubiquitously and constitutively expressed in almost all mammalian cells and is vital for numerous physiological processes. MIF is a pleiotropic inflammatory cytokine important in the upstream regulation of both innate and adaptive immunological responses and has been implicated in the pathogenesis of autoimmune diseases including rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE).

Macrophage migration inhibitory factor (MIF) 相关产品 (2):

目录号 产品名 作用方式 纯度
  • HY-148117
    MD13 Inhibitor
    MD13 是一种巨噬细胞迁移抑制因子 (MIF) 导向的 PROTACKi 值为 71 nM。MD13 可用于癌症研究。
  • HY-D0039
    3-Cyanoumbelliferone Inhibitor
    3-Cyanoumbelliferone 是一种香豆素衍生物,用作分子探针和荧光染料。3-Cyanoumbelliferone 也是巨噬细胞游走抑制因子 (MIF) 互变异构酶抑制剂,Ki 为 2.9 μM。