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  4. MIF2-IN-1

MIF2-IN-1 (compound 5d) 是一种有效的 MIF2 互变异构酶抑制剂，IC50 为 1.0 μM。MIF2-IN-1 通过 MAPK 通路诱导细胞周期停滞来抑制非小细胞肺癌细胞的增殖。MIF2-IN-1 具有研究癌症疾病的潜力。

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MIF2-IN-1 Chemical Structure

MIF2-IN-1 Chemical Structure

CAS No. : 2917525-79-0

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MIF2-IN-1 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

MIF2-IN-1 (compound 5d) is a potent inhibitor of MIF2 tautomerase with an IC50 of 1.0 μM. MIF2-IN-1 suppresses the proliferation of non-small cell lung cancer cells by the induction of cell cycle arrest via deactivation of the MAPK pathway. MIF2-IN-1 has the potential for the research of cancer diseases[1].

IC50 & Target

IC50: 1.0 μM (MIF2)[1]
分子量

480.50

Formula

C26H19F3N2O2S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

MIF2-IN-1 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

MIF2-IN-12917525-79-0OthersMIF2proliferationcell cycle arrestMAPKcancerInhibitorinhibitorinhibit

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