Thymus factor X (Synonyms: 胸腺因子X; TFX-Jelfa)

目录号: HY-P0001 纯度: ≥98.0%: FAQs
Data Sheet SDS COA 产品使用指南

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Thymic factor X (TFX-Jelfa) 是一种来自幼年小牛胸腺的水提取物，也是一种天然的淋巴细胞功能刺激剂。

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Thymus factor X Chemical Structure

CAS No. : 78310-77-7

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生物活性
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参考文献

生物活性

Thymic factor X (TFX-Jelfa) is an aqueous extract from juvenile calf thymuses and a natural stimulator of lymphocyte function^[1]^[2].

体内研究
(In Vivo)

The percentage of necrotic lymphocytes in the spleen in Group I (infected with T. spiralis and treated with Thymus factor X (TFX)) is significantly lower than in the control group on day 7, and approximately the same as in the control group for the rest of the experiment. The percentage of necrotic lymphocytes in muscle tissue in Group I is approximately the same as in the control group on day 7, significantly lower on days 14 and 21 (p<0.0002), approximately the same on days 28 and 35, significantly lower on day 42, and significantly higher on day 60 (p<0.005)^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

CAS 号

78310-77-7

性状

固体

颜色

White to off-white

中文名称

胸腺因子X

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Powder	-20°C	3 years
In solvent	-80°C	6 months
	-20°C	1 month

溶解性数据

In Vitro:

H₂O 中的溶解度 : ≥ 50 mg/mL

* "≥" means soluble, but saturation unknown.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

浓度 _(start)

体积 _(start)

浓度 _(final)

体积 _(final)

动物溶解方案计算器

请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

每只动物的给药体积

μL

动物数量

只

由于实验过程有损耗，建议您多配一只动物的量

计算结果

工作液所需浓度 : mg/mL

该产品水溶性佳，请具体参考实测水 / PBS / Saline 中的溶解度数据。

您所需的储备液浓度超过该产品的实测溶解度，如有需要，请与 MCE 中国技术支持联系。

纯度 & 产品资料

纯度: ≥98.0%

选择批次：

Data Sheet (583 KB) SDS (251 KB)

COA (164 KB)

产品使用指南 (1538 KB)

参考文献

[1]. Piekarska J, et al. Trichinella spiralis: Effect of thymus factor X on apoptosis and necrosis in mice. Exp Parasitol. 2009 Oct;123(2):128-33. [Content Brief]

[2]. Skotnicki AB. Therapeutic application of calf thymus extract (TFX). Med Oncol Tumor Pharmacother. 1989;6(1):31-43. [Content Brief]

Animal Administration ^[1]	The experiment is carried out using 134 mice divided into three groups: Group I: 46 mice infected with T. spiralis and treated with Thymus factor X (TFX); Group II: 42 uninfected mice treated with Thymus factor X; and Control group: 46 mice infected with T. spiralis and not treated with Thymus factor X. Thymus factor X is administered subcutaneously at a dose of 15 mg/kg. The first dose is administered on the third day before the mice are infected with T. spiralis. The dose is repeated at 24 h intervals until the thirteenth day after infection. In all, 17 doses are administered. On days 7, 14, 21, 28, 35, 42, and 60 after infection, six mice from each group are sacrificed using halothane. The spleen, mesenteric lymph nodes and masseter muscles are excised from each mouse and transferred to sterile phospho-buffered saline at 4°C^[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
参考文献	[1]. Piekarska J, et al. Trichinella spiralis: Effect of thymus factor X on apoptosis and necrosis in mice. Exp Parasitol. 2009 Oct;123(2):128-33. [Content Brief] [2]. Skotnicki AB. Therapeutic application of calf thymus extract (TFX). Med Oncol Tumor Pharmacother. 1989;6(1):31-43. [Content Brief]

Animal Administration
^[1]

The experiment is carried out using 134 mice divided into three groups: Group I: 46 mice infected with T. spiralis and treated with Thymus factor X (TFX); Group II: 42 uninfected mice treated with Thymus factor X; and Control group: 46 mice infected with T. spiralis and not treated with Thymus factor X. Thymus factor X is administered subcutaneously at a dose of 15 mg/kg. The first dose is administered on the third day before the mice are infected with T. spiralis. The dose is repeated at 24 h intervals until the thirteenth day after infection. In all, 17 doses are administered. On days 7, 14, 21, 28, 35, 42, and 60 after infection, six mice from each group are sacrificed using halothane. The spleen, mesenteric lymph nodes and masseter muscles are excised from each mouse and transferred to sterile phospho-buffered saline at 4°C^[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

参考文献

[1]. Piekarska J, et al. Trichinella spiralis: Effect of thymus factor X on apoptosis and necrosis in mice. Exp Parasitol. 2009 Oct;123(2):128-33. [Content Brief]

[2]. Skotnicki AB. Therapeutic application of calf thymus extract (TFX). Med Oncol Tumor Pharmacother. 1989;6(1):31-43. [Content Brief]

Help & FAQs

Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Thymus factor X78310-77-7TFX-Jelfa胸腺因子XOthersInhibitorinhibitorinhibit

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Thymus factor X (Synonyms: 胸腺因子X; TFX-Jelfa)

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